Results 231 to 240 of about 1,263,421 (318)

Monodentate Phosphine Modulation in Cyclometallated Platinum(II) Complexes for Antileishmanial, Antiviral, and Antitumor Applications

ChemMedChem, EarlyView.
Schematic representation depicting the influence of phosphine ligand identity on the biological and physicochemical characteristics of Pt(II) complexes: PTA promotes antileishmanial activity, PPh2(Php–COOH) strengthens antiviral activity, and TCEP enhances fluorescence.
Antonio A. de Oliveira‐Neto, Gustavo Clauss, Jennyfer Castro, Marcus S. A. Garcia, Natasha M. Cassani, Bruna C. Sandim, Ana Laura C. Oliveira, Stephanie P. B. Reyes, Nádija N. P. da Silva, Fillipe V. Rocha, Ana C. G. Jardim, Danilo C. Miguel, Camilla Abbehausen   +12 more
wiley   +1 more source

Clinical multimodal Brillouin microscopy-optical coherence elastography system for lens biomechanics. [PDF]

J Biomed Opt
Schumacher J, Zevallos-Delgado C, Rohman L, Schill AW, Singh M, Zhang H, Ruggeri M, Parel JM, Manns F, Larin KV, Scarcelli G.   +10 more
europepmc   +1 more source

Advantages of Exome Sequencing Over Panel Testing for Individuals With a Seizure Indication

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Objective Our aim was to investigate the advantages of exome sequencing versus panel testing for patients with unexplained seizures. Methods We reviewed the diagnostic outcomes of exome sequencing by a commercial genetics laboratory for more than 16 000 individuals with a clinical history of seizures or suspected seizures.
Michelle M. Morrow, Elizabeth Butler, Melanie P. Napier, Lindsay Havens‐Dyer, Annabelle Tuttle, Patricia C. Lopes, Britt A. Johnson, Paul Kruszka, Kirsty McWalter   +8 more
wiley   +1 more source

Assessing the topographic distribution of legacy soil phosphorus in agricultural fields of the Delmarva Peninsula, Mid-Atlantic Coastal Plain, USA. [PDF]

J Environ Qual
Foroughi M, Du L, Scott ISPC, Hively WD, Simpson ZP, Smith ZJ, Hapeman CJ, Rabenhorst MC, Weil RR, McCarty GW.   +9 more
europepmc   +1 more source

A Phase 1, Randomized, Open‐Label, Parallel Group Study to Evaluate the Relative Bioavailability and Safety of Subcutaneous Bepirovirsen when Delivered from a Vial or Prefilled Syringe Fitted with a Safety Syringe Device in Healthy Adult Participants

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Bepirovirsen, an antisense oligonucleotide in development for the treatment of chronic hepatitis B virus (HBV) infection, is administered from glass vials as a subcutaneous (SC) injection by healthcare professionals (HCPs). A ready‐to‐use prefilled syringe (PFS) assembled with a safety syringe device (SSD) has been developed to make ...
Amir S. Youssef, Poonam Shah, Maxwell Hu, Helene Plein, Abhishek Roy, Ravi Sharma, Sarah Mole, Magdalena Blazejczyk, Wendy Cross, Brian Spears, Samuel Pak, Rejbinder Kaur, Robert Elston, Dickens Theodore, Marjan Hezareh, Ahmed Nader   +15 more
wiley   +1 more source

Type 1 Autoimmune Pancreatitis in a Teenager With Ulcerative Colitis: A Case Report. [PDF]

Gastro Hep Adv
Rose JH, Sikorski MJ, Ruane PW, Hudhud D, Al-Sabban AM.   +4 more
europepmc   +1 more source

Evaluation of Edamame Cultivars in New Jersey and Maryland

, 2007
Laura K. Hunsberger, Jim Simón, William Sciarappa, Diandian Shen, Qingli Wu, Brian Hulme   +5 more
openalex   +1 more source

Enhancing Severe Neutropenia Prediction: PKPD‐Informed Labeling for Machine Learning Models Trained on Real‐World Data

Clinical Pharmacology &Therapeutics, EarlyView.
Accurately labeling outcomes in real‐world data for machine learning is challenging due to data sparsity and imbalances. This study developed and evaluated a pharmacokinetic–pharmacodynamic (PKPD)‐informed labeling strategy to enhance the risk prediction of docetaxel‐induced neutropenia.
Conor J O’Hanlon, Jonas Denck, Elif Ozkirimli, Stefanie Bendels, Candice Jamois, Clarisse Chavanne, Dirk Fey, Kimmo Porkka, Oscar Brück, Ken Wang   +9 more
wiley   +1 more source

Treating Acne Scars in Fitzpatrick Skin Types I-VI Using a Novel 1550 nm Non-Ablative Resurfacing Laser With Focal Point Technology. [PDF]

J Cosmet Dermatol
Wang JV, Pomerantz H, Tran TN, Callender V, Weiss R, Weiss M, Bowes L, Geronemus RG.   +7 more
europepmc   +1 more source

The Rhetoric and Reality of English Law in Colonial Maryland, Part 2, 1689-1732 [PDF]

, 2014
Jeffrey K. Sawyer
openalex