Results 231 to 240 of about 1,274,459 (318)

Clinical Study to Evaluate Drug Interactions of Cannabidiol with Citalopram and Morphine in Healthy Adults

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Cannabidiol (CBD) is one of the most abundant bioactive cannabinoids. Research has demonstrated CBD’s ability to inhibit metabolic enzymes like cytochrome P450 (CYP) and UDP‐glucuronosyltransferase (UGT), potentially leading to drug interactions. However, clinical knowledge gaps remain, particularly with regard to drugs that are more commonly taken by ...
Pablo Salcedo   +11 more
wiley   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott   +7 more
wiley   +1 more source

Dr. Sara E. Monaco: A Mentor Extraordinaire Who Changed Cytopathology in Rural Pennsylvania by “Making It the Best”

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT This report introduces Dr. Sara E. Monaco, the incoming President‐Elect of the American Society of Cytopathology (ASC) and System Director of Cytopathology at Geisinger Medical Center. Dr. Monaco has provided significant mentorship to me over the years and facilitated the development of my passion for cytopathology and education.
Terrance J. Lynn
wiley   +1 more source

RORγt‐APCs: The New Masters of Oral Tolerance

open access: yesBarrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source

Myomaker and Myomixer are required for craniofacial myoblast fusion in zebrafish

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Craniofacial and trunk skeletal muscles are derived from different progenitor populations during development. Trunk skeletal muscles contain mostly multinucleated myofibers that are formed through myoblast fusion. However, myoblast fusion in craniofacial muscles and its molecular regulation are not well understood.
Zhanxiong Zhang   +3 more
wiley   +1 more source

Preliminary Evidence of the Association Between Binge Eating and Preeclampsia in Pregnant U.S. Military Active‐Duty Service Women

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objectives Binge eating is the most common disordered eating behavior among pregnant women. This study examined the association of binge‐eating frequency with the presence of a self‐reported current preeclampsia diagnosis in a sample of U.S. military active‐duty Service women. Methods Active‐duty Service women (N = 134), 20–27 weeks gestation,
Ruby Schrag   +10 more
wiley   +1 more source

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