Results 61 to 70 of about 1,215,470 (219)
Scalable manufacturing challenges and limited potency remain two of the most intransigent issues limiting clinical translation of EV therapeutics. Mechanical cues can induce phenotypic changes and increased vesiculation in EV source cells without the use of extraneous reagents, chemicals, and/or cargo, thereby potentially drastically improving the ...
Emily H. Powsner +10 more
wiley +1 more source
Troops and Family Care Fund Feasibility Study [PDF]
Estimates the numbers, needs, and resources of military personnel deployed in or returning from Iraq and/or Afghanistan and their families in the District of Columbia, Maryland, and Virginia.
core
Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors
Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon +10 more
wiley +1 more source
Trade-Off Time: How Four States Continue to Deliver [PDF]
Highlights performance measures used in Indiana, Maryland, Utah, and Virginia to ensure results-driven budgeting by defining goals, assessing priorities and trade-offs, targeting cuts with precision, and creating a culture of results-focused ...
core
Homoisoflavanone (HIF), a bioactive compound isolated from Polygonatum kingianum, selectively suppresses colorectal cancer progression by inducing DNA damage‐mediated mitochondrial apoptosis and parthanatos‐like cell death. HIF triggers mitochondrial dysfunction, including depolarized membrane potential, elevated ROS, and ATP depletion, while impairing
Hongjie Fan +12 more
wiley +1 more source
Design and Characterization of DX‐Tile DNA Nanostar‐Based Hydrogels
In this study, the authors demonstrated that DNA DX‐tile‐based multi‐arm motifs can be used to assemble pure DNA hydrogels, offering greater design flexibility and enhanced control over their mechanical properties and functionalization capabilities compared to single duplex‐based DNA hydrogels.
Dylan V. Scarton +13 more
wiley +1 more source
Strategist of landmark political campaigns from as far away as Liberia and as close as Baltimore City, Professor Larry Gibson takes images from his own storied past and Maryland history to paint a rich ...
Wexler, Laura
core +1 more source
Cryo‐EM analysis reveals an asymmetric MMOH–MMOB complex with distinct protomers, where MMOB binding triggers structural rearrangements from the surface to the active site. This conformational asymmetry shortens the Fe···Fe distance to 2.7 Å in one protomer, forming a geometry suitable for O2 activation and supporting a sequential catalytic mechanism ...
Yunha Hwang +9 more
wiley +1 more source
Fresh-water dinoflagellates of Maryland [PDF]
Collections were made in the summer of 1942 and again at different times in 1946 and 1947. Some collections were not sufficient in numbers to allow for proper identification, so the present paper does not give a complete list.
Thompson, R.H.
core
Doehl et al. discovered an adaptive neuroimmune mechanism that induces itch in tick‐exposed guinea pigs, enabling rapid tick removal. This itch‐induced tick removal (IITR) is mediated by an adaptive cellular immune response and is independent of IgG, IgE, or TRPV1.
Johannes S. P. Doehl +27 more
wiley +1 more source

