Results 71 to 80 of about 3,672 (262)

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Masculinity research and global change

Masculinities and Social Change, 2012
The development of research on masculinity since the 1980s hasproduced rich evidence of the diversity of masculinities. This is now anestablished research field and has had many practical applications. Ithas not yet fully absorbed the wealth of ideas and
Raewyn Connell
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Masculinities in Conservation Science, Policy and Practice: A Qualitative Systematic Review

Conservation Letters
Gender equality is a key target for conservation but is often treated as a women's issue with limited attention to the roles of men and masculinities in perpetuating unequal gender relations.
Simon West, Oliver Lilford, Vanessa Masterson, Emmeline Laszlo Ambjörnsson, Beau Austin, Bram Büscher, Laura‐Bethia Campbell, Marnie Graham, Kuntala Lahiri‐Dutt, Lisen Schultz, Marja Spierenburg, Grace Wong, Carina Wyborn   +12 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Vulnerable masculinities: Implications of gender socialisation in three rural Swazi primary schools

South African Journal of Childhood Education, 2019
Background: This article draws on social constructionism to explore vulnerable boys’ constructions of gender within three primary schools in Swaziland.
Ncamsile D. Motsa, Pholoho J. Morojele
doaj   +1 more source

L'Éternel Masculin

, 2003
Tout comme le féminin, le masculin peut s'envisager comme le résultat d'une construction historique et culturelle, envisagée ici à partir des divers champs des sciences humaines. Distinct du neutre et de l'universel (homo et vir ne sont pas le même homme), face au continent noir du féminin, il a aussi son histoire et ses énigmes.
Tain, Laurence, Mercader, Patricia
openaire   +2 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The African Women Theologians� contribution towards the discussion about alternative masculinities

Verbum et Ecclesia, 2016
In a celebratory mood because of the unparalleled, heroine works of the Circle of Concerned African Female Theologians, from hereon the CIRCLE, I pose to assess their use of critical tools such as alternative masculinities.
Zorodzai Dube
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source