Results 161 to 170 of about 68,003 (260)

Similarity‐Enhanced Representation Learning of Non‐Canonical Amino Acids for Therapeutic Peptide Modeling

Advanced Science, EarlyView.
Non‐canonical amino acids (ncAAs) enhance peptide therapeutics but remain difficult to model computationally. SinCAA, a similarity‐enhanced pretraining framework, jointly optimizes contrastive learning guided by a novel conformational similarity metric with masked node reconstruction, capturing both functional relationships and chemical identity of ...
Chencheng Xu, Lesong Wei, Jianmin Wang, Yuanpeng Xiong, Ruochi Zhang, Yu Wang, Chao Zha, Qiangcheng Zeng, Xin Gao   +8 more
wiley   +1 more source

A Hybrid 2D-3D RGB-D Method for Growth Axis Estimation and Robotic Grasp Pose Generation of Phalaenopsis Orchid Buds. [PDF]

MethodsX
Nguyen TD, Pham MH, Le MH, Ly HH, Nguyen XT, Mac TT, Hoang HH.   +6 more
europepmc   +1 more source

Single‐Molecule Imaging of Endogenous RNA Using a Miniaturized and Circularly Permuted CRISPR‐Cas13 Degron‐Masking System CDegSR

Advanced Science, EarlyView.
CDegSR, a new tool for imaging RNA at single molecule level in living cells was developed by researchers. Background noise was eliminated by protein engineering and making it degrade when not bound to its target. This allowed individual RNA molecules to be clearly imaged and tracked.
Shipeng Shao, Hongchen Zhang
wiley   +1 more source

Large vision model framework for automated C. elegans analysis: From static morphometry to dynamic neural activity. [PDF]

PLoS Comput Biol
Guisnet A, Hendricks M.
europepmc   +1 more source

Tumor Exposomics: A New Paradigm for Individualized Continuous Exposure Monitoring

Advanced Science, EarlyView.
Tumor exposomics integrates continuous monitoring of environmental exposures, endogenous biological responses, and behavioral factors within a unified temporal framework. By combining multimodal sensing technologies with AI‐enabled causal modeling, this emerging paradigm reconstructs exposure‐damage trajectories and supports individualized dynamic risk
Kaicheng Shen, Weiyi Wang, Yang Wang, Yiqiang Wu, Xiaohong Liu, Wei Zhang, Juanjuan Ou   +6 more
wiley   +1 more source

Software-Only Registration and Cross-Spectral Classification of Unsynchronized RGB-LWIR Video: A Multisensor Benchmark for Conveyor-Based Waste Sorting. [PDF]

Sensors (Basel)
Akdemir B, Yuksel SE.
europepmc   +1 more source

Mechanophore‐Based Multichannel Colorimetric Force Sensors: Ultrasound‐Driven Stress and Strain Quantification

Advanced Science, EarlyView.
ABSTRACT Mechanophores with mechanochromic properties have attracted significant attention as force‐responsive materials for structural sensing. However, their applications remain mainly limited to qualitative force visualization, as direct and quantitative extraction of mechanical parameters such as stress and strain from mechanochromic responses has ...
Seungo Baek, Jeong Hoon Rhee, Skylar K. Osler, Minsoo P. Kim, Shyuan Cheng, Leonardo P. Chamorro, Hyunhyub Ko, Maxwell J. Robb, Gun Kim   +8 more
wiley   +1 more source

Protect the Brain When Treating the Heart: Feasibility of 2.5D U-Net for Real-Time Gaseous Microemboli Detection. [PDF]

Bioengineering (Basel)
Angino A, Trotti K, Pizzagalli DU, Krause R, Torre T, Demertzis S.   +5 more
europepmc   +1 more source