Differential expression of microRNA-206 and its target genes in pre-eclampsia [PDF]
Objectives: Pre-eclampsia is a multi-system disease that significantly contributes to maternal and fetal morbidity and mortality. In this study, we used a non-biased microarray approach to identify novel circulating miRNAs in maternal plasma that may be ...
Akehurst, Christine +12 more
core +1 more source
Objective Antiseizure medication (ASM) use during pregnancy has increased over the past decade. However, evidence linking prenatal ASM exposure to neurodevelopmental disorders (NDDs) in offspring remains inconsistent. This study evaluated whether prenatal ASM exposure increases the risk of NDDs in children.
Odile Sheehy +13 more
wiley +1 more source
Automation Process for Morphometric Analysis of Volumetric CT Data from Pulmonary Vasculature in Rats [PDF]
With advances in medical imaging scanners, it has become commonplace to generate large multidimensional datasets. These datasets require tools for a rapid, thorough analysis. To address this need, we have developed an automated algorithm for morphometric
Krenz, Gary S. +2 more
core +2 more sources
Clot Composition Profiling in Large Vessel Occlusion Stroke Via Radiomics
Objective Clot composition may offer insights into the mechanism of ischemic stroke. Radiomics, a noninvasive imaging technique, enables tissue characterization through radiomic features (RFs). We aimed to evaluate clot composition using radiomics on non‐contrast computed tomography (NCCT).
Andres Gudino +23 more
wiley +1 more source
A possible cause of epistaxis: increased masked hypertension prevalence in patients with epistaxis
Introduction Epistaxis and hypertension are frequent conditions in the adult population. Masked hypertension is defined as a clinical condition in which a patient's office blood pressure level is
Baran Acar +6 more
doaj +1 more source
Proteomic prediction and Renin angiotensin aldosterone system Inhibition prevention Of early diabetic nephRopathy in TYpe 2 diabetic patients with normoalbuminuria (PRIORITY): essential study design and rationale of a randomised clinical multicentre trial [PDF]
Introduction: Diabetes mellitus affects 9% of the European population and accounts for 15% of healthcare expenditure, in particular, due to excess costs related to complications.
Beige, Joachim +14 more
core +4 more sources
Response to Is Siesta Masking Masked Hypertension? [PDF]
We thank Ben-Dov and Bursztyn for their interest in our article1 and criticism.1,2 As discussed in our article,1 there are large differences in the prevalence of office resistance and isolated office control depending on many factors, for example, age.
José R. Banegas +4 more
openaire +1 more source
A phase 2 trial of hydroxychloroquine in individuals at risk for rheumatoid arthritis
Background Individuals with serum elevations of anti‐cyclic citrullinated peptide (anti‐CCP) antibodies are at increased risk for future rheumatoid arthritis (RA). No pharmacologic interventions have been approved for the prevention of RA in such ‘at‐risk’ individuals. However, hydroxychloroquine (HCQ) is used without supporting clinical trial evidence.
Kevin D. Deane +33 more
wiley +1 more source
1. ARTERIAL STIFFNESS IN MASKED HYPERTENSION AND TRUE HYPERTENSION
Background: Masked hypertension (MH) has been drawing attention recently because this condition is often seen in untreated and treated individuals and is associated with target organ damage and a poor cardiovascular prognosis.
Young-Soo Lee +9 more
doaj +1 more source
Successful Treatment of a Neonate with Idiopathic Persistent Pulmonary Hypertension with Inhaled Nitric Oxide via Nasal Cannula without Mechanical Ventilation. [PDF]
We report a case study of a term neonate presenting with oxygen desaturation without respiratory distress or acidosis, despite receiving 100% oxygen through a nasal cannula.
Lakshminrusimha, Satyan +2 more
core +2 more sources

