Results 71 to 80 of about 991,088 (288)
A phase 2 trial of hydroxychloroquine in individuals at risk for rheumatoid arthritis
Background Individuals with serum elevations of anti‐cyclic citrullinated peptide (anti‐CCP) antibodies are at increased risk for future rheumatoid arthritis (RA). No pharmacologic interventions have been approved for the prevention of RA in such ‘at‐risk’ individuals. However, hydroxychloroquine (HCQ) is used without supporting clinical trial evidence.
Kevin D. Deane +33 more
wiley +1 more source
Objectives: Our study aimed to estimate the rate of white coat hypertension (WCH) and effect, and masked hypertension in patients attending a tertiary care hospital for 24 hour ambulatory blood pressure monitoring (24-h ABPM).
Khamis Al-Hashmi +7 more
doaj +1 more source
Masked Nocturnal Hypertension: A Complex Phenomenon to Detect in Clinical Practice [PDF]
Fabio Angeli +2 more
openalex +1 more source
Objectives The aim of this study is to generate hypotheses about unknown drugs associated with the onset or worsening of Raynaud's Phenomenon (RP) and to explore their potential pathophysiological mechanisms through a mixed disproportionality/clustering analysis from the WHO pharmacovigilance database.
Alex Hlavaty +4 more
wiley +1 more source
Masked uncontrolled hypertension: Prevalence and predictors
Background: There are limited data on ‘masked uncontrolled hypertension’ (MUCH) in patients with treated and apparently well-controlled BP is unknown. Objectives: To define the prevalence and predictors of MUCH among hypertensive patients with controlled
Ghada Youssef +4 more
doaj +1 more source
Clinical features and predictors of masked uncontrolled hypertension from the Korean Ambulatory Blood Pressure Monitoring Registry [PDF]
Hyun‐Jin Kim +11 more
openalex +1 more source
Involvement of Ca2+ channels in boldine‐induced vascular relaxation. ABSTRACT The regulation of vascular tone plays a fundamental role in blood pressure homeostasis and still represents a significant challenge in clinical practice. Boldine, a naturally occurring alkaloid from Peumus boldus, has emerged as a compound of interest due to its therapeutic ...
Martina Odebrecht Cavichiolo +3 more
wiley +1 more source
Masked nocturnal hypertension as a result of high prevalence of non-dippers among apparently well-controlled hypertensive patients with type 2 diabetes mellitus: data from a prospective study [PDF]
Călin Pop +4 more
openalex +1 more source
ABSTRACT Background Chronic diseases represent a growing public health challenge globally, particularly in developing regions like Sub‐Saharan Africa. Somaliland faces a dual burden of communicable and non‐communicable diseases amidst post‐conflict recovery, yet data on non‐communicable disease (NCD) prevalence and determinants remain scarce.
Abdirahman Omer Ali +5 more
wiley +1 more source
A precision trial case study for heterogeneous treatment effects in obstructive sleep apnea
Abstract Precision medicine tailors treatments to individual patient characteristics, which is especially valuable for obstructive sleep apnea (OSA), where treatment responses vary widely. Traditional trials often overlook subgroup differences, leading to suboptimal recommendations.
Lara Maleyeff +3 more
wiley +1 more source

