Results 81 to 90 of about 205,663 (307)

Effects of sounds of locomotion on speech perception

Noise and Health, 2015
Human locomotion typically creates noise, a possible consequence of which is the masking of sound signals originating in the surroundings. When walking side by side, people often subconsciously synchronize their steps.
Matz Larsson, Seth Reino Ekström, Parivash Ranjbar   +2 more
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

To mask or not to mask

Current trends in Internal Medicine, 2022
Schlegtendal, Anne (Dr. med.), Eitner, Lynn Bernadette (Dr. med.), Falkenstein, Michael (Prof. em. Dr. med. Dipl.-Psych. Dipl.-Ing.), Hoffmann, Anna Sophie (Dr. med.), Lücke, Thomas (Prof. Dr. med.), Sinningen, Kathrin (Dr. throph.), Brinkmann, Folke (Prof. Dr. med.)   +6 more
  +5 more sources

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Improving Masked Autoencoders by Learning Where to Mask

, 2023
14 pages, 8 figures.
Haijian Chen, Wendong Zhang 0002, Yunbo Wang, Xiaokang Yang 0001   +3 more
openaire   +2 more sources

An investigation into the efficacy of methods commonly employed by mix engineers to reduce frequency masking in the mixing of multitrack musical recordings

, 2015
Studio engineers use a variety of techniques to reduce frequency masking between instruments when mixing multi-track musical recordings. This study evaluates the efficacy of three techniques, namely mirrored equalization, frequency spectrum sharing and ...
Wakefield, Jonathan P., Dewey, Christopher   +1 more
core  

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Detectability index measures of binaural masking level difference across populations of inferior colliculus neurons.

, 1997
In everyday life we continually need to detect signals against a background of interfering noise (the “cocktail party effect”): a task that is much easier to accomplish using two ears.
Palmer, AR, McAlpine, D, Jiang, D
core  

Attention in redundancy masking.

Peripheral vision is limited due to several factors, such as visual resolution, crowding, and attention. When attention is not directed towards a stimulus, detection, discrimination, and identification are often compromised.
Coates, Daniel R, Yildirim-Keles, Fazilet Zeynep, Sayim, Bilge   +2 more
core   +1 more source