Results 31 to 40 of about 70,097 (230)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Ion masking improves resolution in quadrupole mass spectrometers [PDF]

, 1973
Mass spectrometers analyze molecular composition by determining mass-to-charge ratio of ion fragments of molecules. Study adds significantly to quantitative understanding of quadrupole mass filter.
Ierokomos, N., Ruecker, M. R.
core   +1 more source

Monaural Singing Voice Separation with Skip-Filtering Connections and Recurrent Inference of Time-Frequency Mask

, 2017
Singing voice separation based on deep learning relies on the usage of time-frequency masking. In many cases the masking process is not a learnable function or is not encapsulated into the deep learning optimization.
Bengio, Yoshua, Drossos, Konstantinos, Mimilakis, Stylianos Ioannis, Santos, João F., Schuller, Gerald, Virtanen, Tuomas   +5 more
core   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Frame Theory for Signal Processing in Psychoacoustics

, 2016
This review chapter aims to strengthen the link between frame theory and signal processing tasks in psychoacoustics. On the one side, the basic concepts of frame theory are presented and some proofs are provided to explain those concepts in some detail ...
A. Bregman, A. Janssen, A. Ron, A.V. Oppenheim, A.V. Oppenheim, B. Laback, B. Laback, B.C.J. Moore, B.C.J. Moore, B.R. Glasberg, C. Heil, C. Heil, C. Wiesmeyr, C.J. Plack, D. Soderquist, D. Wang, D.D. Greenwood, D.T. Stoeva, D.T. Stoeva, E. Hernández, E. Ravelli, E. Zwicker, E. Zwicker, E.A. Lopez-Poveda, G. Chardon, G. Kidd Jr, G. Matz, H. Bölcskei, H. Fastl, I. Daubechies, J. Kovačević, J. Leng, J.J. Benedetto, J.J. O’Donovan, J.S. Garofolo, K. Gröchenig, L. Chai, L.N. Trefethen, M. Bownik, M. Bézat, M. Elad, M. Unoki, M. Vetterli, N. Holighaus, N. Holighaus, N. Perraudin, N.K. Bari, O. Christensen, O. Christensen, O. Christensen, P. Balazs, P. Balazs, P. Balazs, P. Balazs, P. Balazs, P. Balazs, P. Balazs, P. Balazs, P. Casazza, P. Søndergaard, P. Vaidyanathan, P.G. Casazza, P.G. Casazza, R.D. Patterson, R.J. Duffin, R.M. Young, S. Strahl, T. Irino, T. Painter, T. Werther, T.S. Gunawan, W. Jesteadt, X. Valero, X. Zhao, Z. Cvetković   +74 more
core   +1 more source

Exam‐level analysis of lecture capture viewing and student exam performance

FEBS Open Bio, EarlyView.
This study asks how lecture capture relates to exam performance in biology courses with three noncumulative exams. Mixed‐effects modeling separated between‐students from within‐student effects on exam %. Students who watched more recordings earned higher grades, but viewing spikes above a student's own mean, consistent with cramming, predicted small ...
Kirk Hillsley
wiley   +1 more source

Altered Dynamic Functional Network Connectivity in Post‐Stroke Aphasia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Previous studies examining post‐stroke aphasia (PSA) patients via resting‐state functional magnetic resonance imaging (rs‐fMRI) have predominantly focused on static functional connectivity. In contrast, the current investigation aims to elucidate the alterations in dynamic functional network connectivity (dFNC) among PSA patients ...
Guihua Xu, Yongsheng Wu, Junyu Qu, Rui Zhu, Wenwen Xu, Jiaxiang Xin, Dawei Wang   +6 more
wiley   +1 more source

Not one size fits all: a half-mask–based GKRS treatment for preservation of a scalp flap. Illustrative case

Journal of Neurosurgery: Case Lessons
BACKGROUND Implementing the thermoplastic mask as a treatment option in Gamma Knife radiosurgery (GKRS) has madethe discussion of the relative benefits of frame- or mask-based fixation for treatment a frequent occurence. Based on a case review, the authors discuss factors that need to be understood and considered by the treating team.
Victor Goulenko, Venkatesh Shankar Madhugiri, Neil D. Almeida, Matthew B. Podgorsak, Robert A. Fenstermaker, Dheerendra Prasad   +5 more
openaire   +2 more sources

A Systematic Search for X-ray Cavities in the Hot Gas of Galaxy Groups

, 2010
We have performed a systematic search for X-ray cavities in the hot gas of 51 galaxy groups with Chandra archival data. The cavities are identified based on two methods: subtracting an elliptical beta model fitted to the X-ray surface brightness, and ...
Benson, Best, Blanton, Brüggen, Bîrzan, Bîrzan, Cavaliere, Churazov, Condon, Diehl, Diehl, Diehl, Diehl, Dong, Dursi, Fukazawa, Gastaldello, Giacintucci, Humphrey, Jesper Rasmussen, John S. Mulchaey, Jones, Jones, Kraft, Li, Liu, Machacek, McNamara, Mohr, Morita, Nakamura, Nakamura, Nulsen, O’Neill, Rafferty, Rafferty, Randall, Robinson, Ruobing Dong, Scannapieco, Sternberg, Sun, Wise   +42 more
core   +1 more source