Results 81 to 90 of about 1,846,404 (321)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Asymptotic Giant Branch Mass-loss Rates and Metal Yields from Scaled Mixing-length and Mass-loss Parameters

open access: yesThe Astrophysical Journal
Stars on the asymptotic giant branch (AGB) enrich the interstellar medium with carbon, nitrogen, and dust, which in turn boost cooling and promote future generations of planet and star formation.
Ezra Huscher   +2 more
doaj   +1 more source

Mass loss from metal-poor stars [PDF]

open access: yesInternational Astronomical Union Colloquium, 1981
1. IntroductionIt is essential to consider the effect of mass loss to understand the distribution of supergiant stars in the HR diagram. This research concerns the evolution of massive stars with X=0.700 and Z=0.001 during the phases up to central Heexhaustion with the inclusion of mass loss.
C. Chiosi   +3 more
openaire   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Dynamical Interactions and Mass Loss within the Uranian System

open access: yesThe Planetary Science Journal, 2023
The origin and evolution of planetary rings and moons remains an active area of study, particularly as they relate to the impact history and volatile inventory of the outer solar system.
Stephen R. Kane, Zhexing Li
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Assessing Core-powered Mass Loss in the Context of Early Boil-off: Minimal Long-lived Mass Loss for the Sub-Neptune Population

open access: yesThe Astrophysical Journal
We develop a Python-based state-of-the-art sub-Neptune evolution model that incorporates both the post-formation boil-off at young ages ≤1 Myr and long-lived core-powered mass loss (∼Gyr) from interior cooling.
Yao Tang   +2 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Stikine Icefield Mass Loss Between 2000 and 2013/2014

open access: yesFrontiers in Earth Science, 2016
We calculate thinning rates ( frac dh dt ) at the 5,800kmtextsuperscript 2 Stikine Icefield of southeast Alaska fromstacked digital elevation models (DEMs) acquired between 2000 and2013/2014, and glacier velocities between 1985 and 2014 from ...
Andrew K. Melkonian   +3 more
doaj   +1 more source

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