Results 91 to 100 of about 225,747 (287)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

IMPROVING THE METHOD OF OPEN-PIT LIGNITE DEPOSITS DEVELOPMENT IN UKRAINE [PDF]

, 2018
Subject of the research is open-pit mining concerning a full- field industrial development of a number of lignite deposits; feasibility study has been performed for them as for the efficient environmental friendly processing of coal and associated ...
Adamchuk, A.A., Dryzhenko, A.Yu., Shustov, O.O., Адамчук, А.А., Адамчук, Андрей Андреевич, Адамчук, Андрій Андрійович, Дриженко, А.Ю., Дриженко, Анатолий Юрьевич, Дриженко, Анатолій Юрійович, Шустов, Александр Александрович, Шустов, О.О., Шустов, Олександр Олександрович   +11 more
core  

Cosmic rays in early star-forming galaxies and their effects on the interstellar medium [PDF]

, 2017
Galaxies at high redshifts with strong star formation are sources of high-energy cosmic rays. These cosmic rays interact with the baryon and radiation fields of the galactic environment via photo-pair, photo-pion and proton-proton processes to produce ...
Jacobsen, Idunn B., Owen, Ellis R., Surajbali, Pooja, Wu, Kinwah   +3 more
core   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Dynamic Permeability Related to Greisenization Reactions in Sn-W Ore Deposits: Quantitative Petrophysical and Experimental Evidence

Geofluids, 2019
Massive greisens are commonly associated with Sn-W mineralization and constitute low-grade high-tonnage deposits. The formation of this type of deposit results from an intense pervasive metasomatic alteration involving a major fluid and mass transfer ...
Gaëtan Launay, Stanislas Sizaret, Laurent Guillou-Frottier, Colin Fauguerolles, Rémi Champallier, Eric Gloaguen   +5 more
doaj   +1 more source

Accelerator Testing of the General Antiparticle Spectrometer, a Novel Approach to Indirect Dark Matter Detection [PDF]

, 2005
We report on recent accelerator testing of a prototype general antiparticle spectrometer (GAPS). GAPS is a novel approach for indirect dark matter searches that exploits the antideuterons produced in neutralino-neutralino annihilations.
Baret B, C J Hailey, Coutu S, Donato F, Edsjo J, Ellis J Olive K A Santoso Y Spanos V, F Gahbauer, Fuke H, Galaktionov Y V, H T Yu, Halzen F, J E Koglin, K Mori, K P Ziock, L Fabris, Lionetto A M Morselli A Zdravkovic V, N Madden, Picozza P, Profumo S, Rohrer U, T Aramaki, W W Craig, Ziock K P   +22 more
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Resonant neutrino spin-flavor precession and supernova shock revival [PDF]

, 1996
A new mechanism of supernova shock revival is proposed, which involves resonant spin--flavor precession of neutrinos with a transition magnetic moment in the magnetic field of the supernova.
A. Burrows, A. I. Belesev, A. Lanza, A. Yu. Smirnov, B. Cheng, B. Jegerlehner, C. Thompson, C.-S. Lim, C.-S. Lim, D. Nötzold, D. O. Caldwell, D. W. Sciama, D. W. Sciama, E. Kh. Akhmedov, E. Kh. Akhmedov, E. Kh. Akhmedov, E. Kh. Akhmedov, E. Kh. Akhmedov, E. Kh. Akhmedov, G. G. Raffelt, G. G. Raffelt, G. M. Fuller, G. M. Fuller, G. M. Fuller, G. Raffelt, G. Sigl, H. A. Bethe, H. Athar, H.-T. Janka, J. Pulido, J. Schechter, K. Ohta, L. B. Okun, L. Wolfenstein, L. Wolfenstein, M. Fukugita, M. Herant, P. I. Krastev, P. J. Kernan, R. I. Epstein, S. I. Blinnikov, S. I. Blinnikov, S. I. Blinnikov, S. P. Mikheyev, S. P. Mikheyev, S. T. Petcov, S. T. Petcov, S. T. Petcov, V. Castellani, Y-Z. Qian, Y-Z. Qian, Y. Z. Qian, Z. G. Berezhiani   +52 more
core   +4 more sources

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

High Rate Copper Electrodeposition in the Presence of Inorganic Salts

International Journal of Electrochemical Science, 2012
Efforts are on increase for finding out the ways to increase electrodeposition rate. This study shows the effect of using different inorganic salts as accelerators for copper electrodeposition.
H.H. Abdel Rahman, A.H.E. Moustafa, S.M.K. Abdel Magid   +2 more
doaj   +1 more source