Results 71 to 80 of about 232,491 (288)

Tsunamis From Submarine Collapses Along the Eastern Slope of the Gela Basin (Strait of Sicily)

Frontiers in Earth Science, 2021
Geophysical surveys in the eastern slope of the Gela Basin (Strait of Sicily, central Mediterranean) contributed to the identification of several episodes of sediment mass transport, recorded by scars and deposits of various dimensions within the ...
Filippo Zaniboni, Filippo Zaniboni, Gianluca Pagnoni, Maria Ausilia Paparo, Tugdual Gauchery, Tugdual Gauchery, Marzia Rovere, Andrea Argnani, Alberto Armigliato, Stefano Tinti   +9 more
doaj   +1 more source

Overview of technologies for constructing the facilities at the Dniester pumped storage power station [PDF]

, 2019
Purpose. Perform an overview of the construction technologies and substantiate the effectiveness of the Ukrainian experience in building a pumped storage power station (PSPS) on the Dniester River in difficult engineering-geological conditions with the ...
Horbatiuk, Yu, Parinov, V, Petrenko, V, Radkevych, A, Tiutkin, O   +4 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Evidence of slope instability in the Southwestern Adriatic Margin [PDF]

Natural Hazards and Earth System Sciences, 2006
The Southwestern Adriatic Margin (SAM) shows evidence of widespread failure events that generated slide scars up to 10 km wide and extensive slide deposits with run out distances greater than 50 km.
D. Minisini, D. Minisini, F. Trincardi, A. Asioli   +3 more
doaj  

OCEANOGRAPHIC MOWER CRUISE [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2015
The MOWER Cruise has executed a geophysics and geologic expedition in the Gulf of Cádiz (sector adjacent to the Strait of Gibraltar) and west off Portugal, in the framework of the coordinate research project MOWER “Erosive features and associated sandy ...
J. Valencia, G. Ercilla, F. J. Hernández-Molina, D. Casas   +3 more
doaj   +1 more source

Fireside corrosion degradation of ferritic alloys at 600°C in oxy-fired conditions [PDF]

, 2014
This paper reports the results of a study carried out to investigate the effects of simulated coal/biomass combustion conditions on the fireside corrosion. The 1000 h deposit recoat exposure (5 × 200 h cycles) was carried out at 600 °C.
Dudziak, T., Hussain, T., Oakey, J. E., Simms, Nigel J., Syed, A. U.   +4 more
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Impact of volcanism on the sedimentary record of the Neuquén rift basin, Argentina: towards a cause and effect model [PDF]

, 2018
The analysis of volcano-sedimentary infill in sedimentary basins constitutes a challenge for basin analysis and hydrocarbon exploration worldwide. In order to understand the contribution of volcanism to the sedimentary record in rift basins, we study the
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core   +1 more source

Mass-transport deposits on Mediterranean continental margins

, 2007
Extensive mass transport deposits and multiple slide scars testify widespread and recurrent submarine sediment failures occurring during the late Quaternary on the SW-Adriatic and SE-Sicilian margins. These mass movements and their consequences contributed to shape the continental slopes and fill the basins with characteristic signatures ...
openaire   +2 more sources