Results 131 to 140 of about 12,692,806 (311)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
State College Times, October 25, 1933 [PDF]
Volume 22, Issue 20https://scholarworks.sjsu.edu/spartandaily/12914/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Spartan Daily, October 14, 1947 [PDF]
Volume 36, Issue 9https://scholarworks.sjsu.edu/spartandaily/9029/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core +7 more sources
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Spartan Daily, October 23, 1947 [PDF]
Volume 36, Issue 16https://scholarworks.sjsu.edu/spartandaily/9035/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Spartan Daily, February 20, 2001 [PDF]
Volume 116, Issue 18https://scholarworks.sjsu.edu/spartandaily/9654/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Spartan Daily, February 24, 2005 [PDF]
Volume 124, Issue 20https://scholarworks.sjsu.edu/spartandaily/10092/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core +1 more source

