Results 31 to 40 of about 49,417 (261)
Journal of Materials Research and Technology, 2022 In the present paper, we report a comprehensive theoretical study dealing with γ -ray, fast and thermal neutrons shielding features of compositionally graded Pb-free lithium borate glasses doped barite: (B2O3)(0.6)(BaSO4)(x)(Li2O)(0.4-x).
Norah A.M. Alsaif +7 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Advances in Civil Engineering, 2020 In the drilling and blasting excavation of underground rock mass, the stress wave produced by the blasting holes usually propagates in the form of cylindrical wave, while the rock mass surrounding the underground engineering is initially subjected to the
Qian Dong, XinPing Li, JunHong Huang
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
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Effective density and mass attenuation coefficient for building material in Brazil
Applied Radiation and Isotopes, 2006 This paper presents values for density and mass attenuation coefficient of building materials commonly used in Brazil. Transmission measurements were performed to provide input information for simulations with MCNP4B code. The structure for the clay bricks was simulated as a mix of all material layers and an effective density determined.
/Salinas, I. C. P. +2 more
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CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng +4 more
wiley +1 more source
Radiation Protection and Environment, 2019 An attempt has been made to prepare the nonlead-based gamma shielding materials by adding different weight percentages (0%, 10%, 20%, and 40%) of bismuth in high-density polyethylene (HDPE) matrix.
M Sheela +3 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Factors associated with relapse course and disability in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) remain incompletely understood. Objectives To identify clinical and modifiable factors associated with relapse and disability in MOGAD. Methods In this ambispective multicentre cohort study using data from
Yingtao Wang +23 more
wiley +1 more source