Results 201 to 210 of about 5,413,419 (288)

Myostatin/Smad3 in Spinal Muscular Atrophy: Biomarkers of Disease Severity and Treatment Response

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Given the role of Myostatin (MSTN) in muscle homeostasis and its modulation by current spinal muscular atrophy (SMA) therapies, we investigated serum MSTN and, for the first time, its downstream effector Smad3 as candidate non‐invasive biomarkers in SMA patients undergoing disease‐modifying therapies (DMTs).
Giorgia Riolo, Claudia Dosi, Stefano Parravicini, Riccardo Zanin, Marta Cheli, Eleonora Giacopuzzi Grigoli, Amalia Canciello, Francesca Andreetta, Riccardo Masson, Silvia Bonanno, Stefania Marcuzzo, Lorenzo Maggi   +11 more
wiley   +1 more source

Climatic controls on surface albedo and mass balance of Urumqi Glacier No. 1 in the last decade, 2014-2024. [PDF]

iScience
Yuhan H, Feiteng W, Chunxiang Z, Ruiqi P, Zhencai D, Jing M.   +5 more
europepmc   +1 more source

Mapping the Social Network Structure and Composition of Black Individuals With Rheumatic and Musculoskeletal Conditions

Arthritis Care &Research, EarlyView.
Objective Our objective was to describe the social networks of Black individuals with rheumatic and musculoskeletal conditions and understand the clustering of health‐related behaviors to inform future community‐based, peer‐led interventions. Methods We used an adapted Personal Network Survey for Clinical Research (PERSNET) to map the personal social ...
Taussia Boadi, Amar Dhand, Leah Santacroce, Neil Pillai, Komel Safdar, Mia T. Chandler, Ariel Childs, Monica Crespo‐Bosque, Gina Curry, Mary Dollear, Alice Eggleston, Daniel Erickson, Dieufort Fleurissaint, Denice Garrett, Gail Granville, Tyler Green, Magdalena Hamielec, Elena Losina, Karen Mancera‐Cuevas, Mary Ann Nelson, Chisa Nosamiefan, Bisola Ojikutu, Tonya S. Roberson, Mary Beth Son, Marie Jacques Toussaint, Michael York, Rosalind Ramsey‐Goldman, Candace H. Feldman   +27 more
wiley   +1 more source

Mass balance study of [¹⁴C]-ABBV-552, a synaptic vesicle glycoprotein 2A positive modulator, in healthy male participants following single oral dose administration. [PDF]

Eur J Clin Pharmacol
Miles N, McNamee B, Soleman SI, Zadikoff C, Boiser J, Laplanche L, Burton R, Shebley M, Boinpally RR.   +8 more
europepmc   +1 more source

Prevalence of Dietary Supplement Use and Potential Medication Interactions Among Adults With Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize the prevalence and correlates of dietary supplement use, identify commonly used supplements, and evaluate potential supplement–medication interactions among adults with systemic lupus erythematosus (SLE).
Sarah L. Patterson, Russell Ellyson, Jessica Fitzpatrick, Ghizlane Yaakoubi, Bradley Pearce, S. Sam Lim, Jinoos Yazdany, Laura C. Plantinga   +7 more
wiley   +1 more source

Submarine groundwater discharge and associated fluxes along the Kanyakumari coast of India using radon and nutrient mass balance approach. [PDF]

Sci Rep
George AK, Gandhi MS, Muthukumar P, Roy PD, Baalamurugan A, Jothimani M, Selvam S.   +6 more
europepmc   +1 more source

Real‐World Safety of Concomitant Colchicine and Statin Therapy

Arthritis Care &Research, EarlyView.
Objective This study aimed to evaluate the risk of clinically meaningful muscle‐ and liver‐related outcomes associated with concomitant colchicine–statin therapy in a real‐world setting, and to determine whether concomitant therapy increases the incidence of toxicity compared with either agent alone.
Roni Meidan, Ranel Loutati, Dan Caspi, Ori Elkayam, Ran Abuhasira, Tali Eviatar   +5 more
wiley   +1 more source

Unravelling the human disposition of [¹⁴C]-vebreltinib: Faecal recovery of parent drug and a major circulating metabolite defines its mass balance profile. [PDF]

Br J Clin Pharmacol
Li L, Xue W, Yin H, Gao Q, Wu J, Shi H, Zhang P, Dong R.   +7 more
europepmc   +1 more source

Positive Affect Is Associated With Better Physical Function in Early Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective This study examined the association between positive affect and physical function in individuals with early rheumatoid arthritis (RA). Methods We analyzed baseline data from 129 adults with early RA (persistent joint symptoms for ≤24 months) and active disease enrolled in the Central Pain in RA 2 (CPIRA‐2) study.
Burcu Aydemir, Jing Song, Lutfiyya N. Muhammad, Wendy Marder, Kevin Deane, Clifton Bingham, Lisa A. Mandl, Robert Edwards, Judith T. Moskowitz, Yvonne C. Lee   +9 more
wiley   +1 more source

Predicting vegetative phase nutrient uptake in <i>Cannabis sativa</i> L. via transpiration-driven mass-balance. [PDF]

Front Plant Sci
Powell K, Bauerle WL.
europepmc   +1 more source