Results 81 to 90 of about 1,208,459 (306)

Fantastic Corporeality of the Political Process (on the Example of Cinematic Material)

open access: yesCorpus Mundi
The article is devoted to the analysis of mythological foundations of mass culture and their role in the formation of political discourse through the images of fantastic characters reflecting archetypal motifs and emotionally affecting the collective ...
Ivan V. Suslov
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Nietzsche’s Critique of Mass Culture

open access: yesInternational Studies in Philosophy, 1999
Etude de la critique de la culture moderne et de ses aspects negateurs de la vie chez Nietzsche. Developpant contre la religion, la morale, les institutions et les valeurs des societes modernes, une critique inspiree des Lumieres et du vitalisme romantique, Nietzsche elabore une des premieres critiques de la culture de masse et de la societe au nom d ...
openaire   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Relationship Between Mass Media and Mass Culture: Frankfurt School and Cultural Studies School

open access: yes, 2016
Mass media and mass culture are probably the two most frequently used terms to depict the current human life in most parts of the world. In the light of definitions available the article first reviews mass media and mass culture historically.
LIU, Zhen
core  

Dustin Kidd: Pop Culture Freaks [Audio interview]

open access: yes
Dustin Kidd published Pop Culture Freaks: Identity, Mass Media, and Society in 2014 with Westview Press. It’s a hybrid work that combines original research, theoretical and methodological perspectives, and some of the features you might find in a ...
Rowland, Fred, Kidd, Dustin
core   +1 more source

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