Results 141 to 150 of about 26,344 (283)

ITGB1 Regulates Triple‐Negative Breast Cancer Development by Modulating the Tumor Microenvironment

Advanced Science, EarlyView.
ABSTRACT Tumorigenesis and metastasis are frequently attributed to the intricate interplay between cancer cells and the tumor microenvironment (TME). Comprehending the mechanisms and key regulators of cancer‐immune crosstalk in the TME is imperative for developing efficacious immunotherapy.
Nuozi Song, Siqi Chen, Lei Wang, Jessica Dang, Xu Cao, Stephanie Singh, Lu Yang, Jinhui Wang, Steven T. Rosen, Yingyu Wang, Chun‐Wei D. Chen, Cheng Zhang, Mingye Feng   +12 more
wiley   +1 more source

Mixed methods to evaluate knowledge, attitudes and practices (KAP) towards rabies in central and remote communities of Moramanga district, Madagascar.

PLoS Neglected Tropical Diseases
Control of dog-mediated rabies relies on raising awareness, access to post-exposure prophylaxis (PEP) and mass dog vaccination. To assess rabies awareness in Moramanga district, Madagascar, where rabies is endemic, two complementary quantitative and ...
Claire Leblanc, Daouda Kassié, Mendrika Ranaivoharimina, Elliot Fara Nandrasana Rakotomanana, Reziky Tiandraza Mangahasimbola, Anjasoa Randrianarijaona, Ravo Ramiandrasoa, Alphonse José Nely, Nivohanitra Perle Razafindraibe, Soa Fy Andriamandimby, Dany Bakoly Ranoaritiana, Virginie Rajaonarivony, Laurence Randrianasolo, Laurence Baril, Chiarella Mattern, Rila Ratovoson, Hélène Guis   +16 more
doaj   +1 more source

Spartan Daily, March 8, 2007 [PDF]

, 2007
Volume 128, Issue 25https://scholarworks.sjsu.edu/spartandaily/10339/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core   +1 more source

Fermented Lacticaseibacillus Paracasei Cultures Ameliorate Colitis by Modulating Microbiota‐Derived Tryptophan Metabolism and Macrophage Polarization

Advanced Science, EarlyView.
A solid‐state fermented probiotic (PYW) is developed using wheat bran as substrate, containing high viable Lacticaseibacillus paracasei and bioactive metabolites. PYW alleviates intestinal inflammation by gut microbiota composition, enriching indole derivatives, activating aryl hydrocarbon receptor signaling, and regulating macrophage polarization. PYW
Heng Zhang, Jingzhou Sun, Xin Zheng, Huiqing Yang, Aowen Xie, Yuxuan Ding, Yuxia Mei, Jinshan Li, Yuanliang Hu, Min Ren, Yangyang Liu, Yunxiang Liang   +11 more
wiley   +1 more source

Mass vaccination of dogs, control of canine populations and post‐exposure vaccination – necessary but not sufficient for achieving childhood rabies elimination [PDF]

Tropical Medicine & International Health, 2015
D N, Durrheim, H, Rees, D J, Briggs, L H, Blumberg   +3 more
openaire   +2 more sources

PDIA3 Inhibition Facilitates Sensitivity of IKE‐Induced Ferroptosis via STAT3/LCN2 Axis to Improve Glioblastoma Therapy

Advanced Science, EarlyView.
In this manuscript, protein disulfide isomerase A3 (PDIA3) is identified as a key factor mediating the susceptibility of ferroptosis in GBM. Inhibition of PDIA3 enhances IKE or cystine starvation‐induced ferroptosis in GBM cells by resulting in the accumulation of lipid peroxidation and a reduction in GSH level.
Jie Zhang, Wei Wang, Xin Liu, Peifen Lu, Xinjing Liu, Qiucheng Nie, Siyuan Xin, Hong Li, Donglin Yu, Xinyue Zhang, Kailong Li, Xiaomin Han, Shuping Zhang, Wei Chong, Lili Sun, Wei Li, Tao Xin, Jin Jiao, Qiang Ma, Yiju Wei   +19 more
wiley   +1 more source

Additional file 1 of Evaluation of the immune response of dogs after a mass vaccination campaign against rabies in Tunisia

Additional file 1 Datasheet 1: Household questionnaire.
Handous, Mariem, Turki, Imed, Ghram, Abdejelil, BenMaiz, Samia, Bensalem, Jihen, Basdouri, Nourhene, Soltani, Mohamed, Bassalah, Farah, Kharmachi, Habib   +8 more
openaire   +1 more source

Mutual Exclusion Analysis Shows that DUSP9 Negatively Regulates PD‐L1 Expression and Acts as a Target to Enhance Anti‐PD‐1 Efficacy

Advanced Science, EarlyView.
A mutually exclusive screening system is established to identify negative regulators of highly plastic genes. Dual specificity phosphatase (DUSP9) is a novel negative regulatory molecule of PD‐L1 by dephosphorylating STAT3, and acts as a target molecule in combination with PD‐1 antibody for tumor immunotherapy and a new clinical biomarker for ...
Yuzhe Hu, Ling Tang, Zheng Kuang, Danyi Huang, Ting Li, Gaofei Yin, Yingyu Chen, Wei Guo, Wenling Han, Pingzhang Wang   +9 more
wiley   +1 more source

Irradiated Tumor Cell‐Derived Microparticles Activate Systemic Anti‐Tumor Immunity via the STING/NLRP3/GSDMD Axis in Neutrophils

Advanced Science, EarlyView.
Radiotherapy induces tumor cells to release microparticles (RT‐MPs) into the circulation. The mitochondrial DNA carried by these RT‐MPs activates the STING/NLRP3/GSDMD axis in splenic neutrophils, triggering IL‐1β secretion. This, in turn, enhances dendritic cell function and facilitates the formation of cytotoxic T lymphocytes, thereby promoting ...
Yan Hu, Jiacheng Wang, Mengjie Che, Zheng Yang, Jingshu Meng, Xiao Yang, Yue Deng, Zhiyuan Zhou, Yijun Wang, Wenwen Wei, Zhanjie Zhang, Bian Wu, You Qin, Kunyu Yang, Honglin Jin, Fang Huang, Yajie Sun, Lu Wen, Chao Wan   +18 more
wiley   +1 more source

Kerugian Ekonomi Akibat Penyakit Rabies di Provinsi Nusa Tenggara Timur (ECONOMICAL LOSSES OF RABIES DISEASE IN EAST NUSA TENGGARA PROVINCE)

Jurnal Veteriner, 2013
The objective of this paper was to analyze economic impact of rabies in East Nusa Tenggara Province.Data from Health Department of East Nusa Tenggara Province (Period 1998-2007) were applied to a setof link the economics model. Analysis presented in this
Ewaldus Wera, Maria Geong, Maxs Urias Ebenhaizar Sanam   +2 more
doaj