Results 221 to 230 of about 26,221 (285)

Animal Rabies in Kazakhstan: Stable Endemicity, Surveillance Pitfalls, and Priority Actions. [PDF]

Pathogens
Abdrakhmanov SK, Abenova AZ, Mukhanbetkaliyeva AA, Korennoy FI, Perez AM.   +4 more
europepmc   +1 more source

Purification, Fluorescent Labeling, and Detyrosination of Mammalian Cell Tubulin for Biochemical Assays

Cytoskeleton, EarlyView.
ABSTRACT Microtubules play essential roles in numerous cellular processes. All microtubules are built from the protein tubulin, yet individual microtubules can differ spatially and temporally due to their tubulin isotype composition and post‐translational modifications (PTMs).
Ezekiel C. Thomas, Yang Yue, Morgan L. Pimm, Takashi Hotta, Ryoma Ohi, Kristen J. Verhey   +5 more
wiley   +1 more source

Rabies and Pinnipeds Reviewed: Premonitions, Perturbations, and Projections? [PDF]

Vet Sci
Rupprecht CE, Belsare AV.
europepmc   +1 more source

Protocol for Reconstituting Adaptor‐Mediated Activation of Full‐Length Kinesin‐1

Cytoskeleton, EarlyView.
ABSTRACT Kinesin‐1 is a member of the kinesin superfamily that plays an essential role in intracellular cargo transport. In the absence of cargo, Kinesin‐1 exhibits low motor activity due to autoinhibition. Multiple studies have demonstrated that adaptor proteins, which link cargos to Kinesin‐1, can activate Kinesin‐1 by releasing the autoinhibition ...
Haruka Masumoto, Kyoko Chiba
wiley   +1 more source

Community knowledge, practices, and dog management toward rabies in Hung Yen province, Vietnam: Insights for strengthening One Health interventions toward the 2030 zero-death goal. [PDF]

Vet World
Vu TTT, Mai TN, Dong VH, Truong HT, Tran TT, Tiwari HK.   +5 more
europepmc   +1 more source

Global gene expression profiling of virulent and attenuated strains of Ehrlichia ruminantium: Toward the comprehension of pathogenesis [PDF]

, 2014
Emboule, Loïc, Gordon, Jonathan, Lebrigand, Kevin, Lefrançois, Thierry, Marcelino, Isabel, Mari, Bernard, Martinez, Dominique, Meyer, Damien, Pinarello, Valérie, Pruneau, Ludovic, Sheikboudou, Christian, Vachiery, Nathalie, Viari, Alain   +12 more
core  

Expression, Purification, and Microscopy‐Based Assays for Engineered Recombinant Tyrosinated, Detyrosinated, and Δ2 Human Tubulin

Cytoskeleton, EarlyView.
ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen, Agnieska Szyk, Antonina Roll‐Mecak   +2 more
wiley   +1 more source

Rabies elimination in the WHO African Region. [PDF]

Bull World Health Organ
Zinsstag J, Alimi Y, Mettenleiter TC, Boussini H, Salih H.   +4 more
europepmc   +1 more source

Optimal Dose and Safety of Intravenous Favipiravir in Hospitalized Patients With COVID‐19: A Dose‐Escalating, Randomized Controlled Phase Ib Study

Clinical Pharmacology &Therapeutics, EarlyView.
AGILE (NCT04746183) is a Phase Ib/IIa platform, evaluating candidates to treat COVID‐19. Candidate Specific Trial 6 evaluated the safety and optimal dose of a novel intravenous formulation of favipiravir in a dose‐escalating, open‐label, randomized, controlled, Bayesian adaptive Phase Ib trial.
Tim Rowland, Richard FitzGerald, Elizabeth Challenger, Laura Dickinson, Laura J. Else, Lauren Walker, Colin Hale, Victoria Shaw, Callum Kelly, Rebecca Lyon, Jennifer Gibney, Karim Dhamani, Margaret Irwin, Yvanne Enever, Michelle Tetlow, William Wood, Helen Reynolds, Justin Chiong, Orod Osanlou, Henry Pertinez, Katie Bullock, William Greenhalf, Andrew Owen, David G. Lalloo, Michael Jacobs, Julian A. Hiscox, Thomas Jaki, Pavel Mozgunov, Geoffrey Saunders, Gareth Griffiths, Saye H. Khoo, Thomas E. Fletcher, on behalf of the AGILE CST‐6 Study Group, Shazaad Ahmad, Christopher J. Edwards, Lesley Dry, Georgie McKenzie, Aleksandra Ros, Michael Stackpoole, Laura Bradley, Karen Jennings‐Wilding, Nicholas Paton, Fred Hayden, Janet Darbyshire, Amy Lucas, Ulrika Lorch, Andrew Freedman, Richard Knight, Steven Julious   +48 more
wiley   +1 more source

Rabies threatens as a preventable viral disease with persistent control barriers: one health approach suggested as a rightful intervention. [PDF]

Ann Med Surg (Lond)
Kumar S, Pattnaik R, Mishra S, Rout A, Mohapatra RK, Tuglo LS.   +5 more
europepmc   +1 more source