Results 51 to 60 of about 31,577 (240)

Estimating the Size of Dog Populations in Tanzania to Inform Rabies Control

Veterinary Sciences, 2018
Estimates of dog population sizes are a prerequisite for delivering effective canine rabies control. However, dog population sizes are generally unknown in most rabies-endemic areas.
Maganga Sambo, Katie Hampson, Joel Changalucha, Sarah Cleaveland, Tiziana Lembo, Kennedy Lushasi, Eberhard Mbunda, Zacharia Mtema, Lwitiko Sikana, Paul C.D. Johnson   +9 more
doaj   +1 more source

Mass Dog Vaccination and Animal Birth Control: A One Health Pilot Project in Karachi, Pakistan

, 2023
The Sindh province in Southern Pakistan reports staggering numbers of dog bites. Not only to treat but to prevent, dog-bite casualties, in January 2018, the Indus Hospital launched a proof of concept of One Health. The pilot project ‘Rabies Free Pakistan’ (RFP) consisted of the performance of mass dog vaccination (MDV) and animal birth control (ABC) in
Salahuddin, Naseem, Baig-Ansari, Naila, Aftab Gohar, M., Khan, Rabia M., Javed, Wajiha, Abbas Jaffari, S. Anzal, Mahmood, Qamer, Ahmad, Manzoor, Ullah, Muhammad Rafi, Ahmad, Fiaz, Ahmad, Waqas   +10 more
openaire   +2 more sources

Every Dog Has Its Data: Evaluation of a Technology-Aided Canine Rabies Vaccination Campaign to Implement a Microplanning Approach

Frontiers in Public Health, 2021
Background: Robust dog vaccination coverage is the primary way to eliminate canine rabies. Haiti conducts annual canine mass vaccination campaigns, but still has the most human deaths in the Latin American and Caribbean region. We conducted an evaluation
B. Monroe, Fleurinord Ludder, Pierre Dilius, Kelly Crowdis, F. Lohr, J. Cleaton, L. Gamble, J. Blanton, Melissa D. Etheart, E. Pieracci, Marco Antonio Natal Vigilato, B. Molina-flores, M. Millien, A. Gibson, R. Wallace   +14 more
semanticscholar   +1 more source

Modelling canine rabies elimination in India through mass dog vaccination

, 2022
The ‘Zero by 30’ campaign aims to globally eliminate dog-mediated human rabies deaths by 2030. Theoretical and empirical studies have shown that annual mass rabies vaccination (MRV) campaigns that vaccinate at least 70% of the dog population in an area can effectively control canine rabies outbreaks and eventually eliminate it. Achieving such coverages
openaire   +2 more sources

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Volunteer based approach to dog vaccination campaigns to eliminate human rabies: Lessons from Laikipia County, Kenya

PLoS Neglected Tropical Diseases, 2020
Background An estimated 59,000 people die from rabies annually, with 99% of those deaths attributable to bites from domestic dogs (Canis lupus familiaris).
Adam W. Ferguson, D. Muloi, Dedan K. Ngatia, Wangechi Kiongo, Duncan M Kimuyu, P. Webala, M. Olum, M. Muturi, S. Thumbi, R. Woodroffe, Lucy Murugi, E. Fèvre, S. Murray, D. Martins   +13 more
semanticscholar   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Development of a high number, high coverage dog rabies vaccination programme in Sri Lanka

BMC Infectious Diseases, 2019
Background Rabies is estimated to cause 59,000 deaths and economic losses of US$8.6 billion every year. Despite several years of rabies surveillance and awareness programmes, increased availability of post-exposure prophylaxis vaccinations and dog ...
Carlos Sánchez-Soriano, Andrew D. Gibson, Luke Gamble, Jordana L. Burdon Bailey, Samantha Green, Mark Green, Barend M. deC. Bronsvoort, Ian G. Handel, Richard J. Mellanby, Stella Mazeri   +9 more
doaj   +1 more source

Tuning Mechanoreceptor Signaling Enhances the Adjuvant Effect of Biomaterial Vaccines

Advanced Functional Materials, EarlyView.
Matrix stiffness serves as an independent immunological signal in biomaterial vaccines. Stiffer microporous hydrogel vaccines enhance dendritic cell maturation and migration to draining lymph nodes, promote T follicular helper cell expansion through Yap/Taz signaling, and increase antigen‐specific antibody production.
Lily Shang, Daniel P. Mayer, Prabhat K. Purbey, Yingzi Liu, Kindra Kelly‐Scumpia, Clara Kang, Natalie Tsubamoto, Dhriti Bolangadi, Iqra Arshad, Charisse Ng, Maksim V. Plikus, Dino Di Carlo, Jason S. Weinstein, Philip O. Scumpia   +13 more
wiley   +1 more source