Results 31 to 40 of about 777,404 (312)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

A model for mass customization and flexibility in mass housing units

Open House International, 2021
Purpose This paper aims to present a mass customization model for interior spaces of mass housing projects to provide solutions that will increase flexibility in accordance with different user needs. Design/methodology/approach The research project develops a model that generates an expert system that leads to different spatial variations.
Garip, Ervin, Onay, Nilufer Saglar, Garip, S. Banu   +2 more
openaire   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Real-Time Ventilation Measurements from Mechanically Ventilated Livestock Buildings for Emission Rate Estimations [PDF]

, 2004
A six-state USDA-IFAFS funded research project (Aerial Pollutant Emissions from Confined Animal Buildings, APECAB) was conducted with the purpose of determining hydrogen sulfide, ammonia, PM10, and odor emission rates from selected swine and poultry ...
Baek, B., Balota, A., Baughman, G., Beasley, D., Bundy, Dwaine, Goodrich, P., Heber, Albert, Hetchler, Brian, Hoff, Steven, Hoff, Steven, Huebner, M., Jacobson, Larry, Jerez, S., Johnson, V., Koziel, Jacek, Koziel, Jacek, Lim, T., McClure, J., Munilla, R., Ni, Ji-Qin, Nicolai, R., Roberts, M., Schmidt, David, Spinhirne, J., Sweeten, J., Tao, P., Zelle, B., Zhang, Y.   +27 more
core   +3 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Hybrid Study of Quantitative–Qualitative Analysis to Recognize the Most Cost-Effectiveness Criteria to Develop Affordable Mass Housing

Buildings
Nowadays, providing housing for the low-income groups of society is a concern for governments, especially in developing nations. An attempt has been made to recognize the most significant real criteria for reducing housing project costs and providing ...
Amir Faraji, Tahereh Meydani Haji Agha, Shima Homayoon Arya, Elnaz Ghasemi, Payam Rahnamayiezekavat   +4 more
doaj   +1 more source

Source identification and quantification of particulate matter emitted from livestock houses [PDF]

, 2010
There is need to identify and quantify the contribution of different sources to airborne particulate matter (PM) emissions from animal houses. To this end, we compared the chemical and morphological characteristics of fine and coarse PM from known ...
Aarnink, A.J.A., Cambra-López, M., Hermosilla, T., Lai, T.L.H., Montero, M., Ogink, N.W.M.   +5 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

To the problem of development of low-rise housing in Russia [PDF]

E3S Web of Conferences, 2019
The issue of providing the population with comfortable and affordable housing has always been rather acute in our country. The solution to this problem, taking into account the trends in the creation and transformation of the urban environment into the ...
Tusnina Valentina, Yakovleva Ekaterina
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source