Results 71 to 80 of about 4,973,131 (354)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Ideals of city planing in the soviet period / Sovietinio periodo miestų planavimo idealai

open access: yesMokslas: Lietuvos Ateitis, 2013
The text is focused on ideals and values hidden under the Soviet period city planning. Soviet urban planning visions of the first half of the 20th century were balancing between naive fiction and visionary concepts.
Matas Šiupšinskas, Ieva Cicėnaitė
doaj  

Mass spectrometer with magnetic pole pieces providing the magnetic fields for both the magnetic sector and an ion-type vacuum pump [PDF]

open access: yes, 1976
A mass spectrometer (MS) with unique magnetic pole pieces which provide a homogenous magnetic field across the gap of the MS magnetic sector as well as the magnetic field across an ion-type vacuum pump is disclosed.
Giffin, C. E.   +2 more
core   +1 more source

Survey on the user satisfaction with the mass housing projects led by district municipality: Konya-Karatay example

open access: yesGAZI UNIVERSITY JOURNAL OF SCIENCE, 2020
Mass housing played an important role in changing the face of the cities. The Municipality Law No.5393 which gave the right to municipalities to build mass housing were factors that have accelerated the mass housing production.
Betül Hatipoğlu Şahin, Aysegul Tereci
semanticscholar   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Outgassing, Temperature Gradients and the Radiometer Effect in LISA: A Torsion Pendulum Investigation [PDF]

open access: yes, 2006
Thermal modeling of the LISA gravitational reference sensor (GRS) includes such effects as outgassing from the proof mass and its housing and the radiometer effect.
Gundlach, Jens H   +2 more
core   +4 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Konut ve Site Alanlarında Uygulanan Peyzaj Tasarımlarının Yeterliliği Üzerine Bir Araştırma: Tekirdağ Kenti

open access: yesDüzce University Faculty of Forestry Journal of Forestry, 2016
Yaşadığımız kentlerde, sağlıksız büyümenin getirdiği sorunlara çözüm arayışı, bireylerin ve toplumun gereksinimlerinin nasıl karşılanacağı, kentlerin temel sorunlarının kaynağını oluşturmaktadır.
Murat Özyavuz, Yasin Dönmez
doaj  

AN EMPIRICAL ASSESSMENT OF INEFFECTIVE COMMUNICATION INHERENT IN THE ATTRIBUTES OF MASS HOUSING PROJECTS

open access: yesJournal of Construction Project Management and Innovation, 2015
Mass housing projects (MHPs) continue to experience significant communication difficulties among the project teams in their delivery which is largely perceived to be due to the influence of its unique characteristics.
Titus E. KWOFIE   +2 more
doaj   +1 more source

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