Results 201 to 210 of about 1,066,264 (303)

Erysipelothrix rhusiopathiae clone reemergence in association with a multi-year mass mortality event in high Arctic muskoxen (Ovibos moschatus). [PDF]

Sci Rep
Wooten MT, Forde TL, Roberto-Charron A, Fredlund M, Mullin T, Christensen OA, Schneider A, Radhakrishnan S, Goldsmith D, Morrison B, Lau E, Mavrot F, Seru LV, Fang T, Donovan RM, Cluff HD, van der Meer F, Kutz SJ.   +17 more
europepmc   +1 more source

Rational Design of Broad‐Spectrum Anti‐Enteroviral Molecular Glues Targeting Enteroviral RNAi Suppressors

Advanced Science, EarlyView.
By leveraging this homodimerization mechanism, molecular glues were rationally designed to induce dysfunctional 3A dimerization, thereby restoring antiviral RNAi. The optimal molecular glue, VTP‐32, demonstrated potent and pan‐enterovirus (groups A, B, D) antiviral effects.
Yuan Fang, Xiong Xie, Huidi Fan, Botao Wu, An Wang, Wenhao Dai, Zezhong Liu, Jian Li, Huoyan Tong, Jianan Li, Yujie Ren, Jinlin Wang, Xi Zhou, Hong Liu   +13 more
wiley   +1 more source

Detection of Two High Pathogenicity Avian Influenza Virus (HPAIV) Subtypes, H5N1 and H5N5, in a Mass Mortality Event in Wild Seabirds and Co-Location With Dead Seals. [PDF]

Transbound Emerg Dis
Falchieri M, Bentley E, Coombes HA, Mollett BC, Terrey J, Holland S, Stubbings E, Mcginn N, Cooper J, Ahmad S, Lewis J, Clifton B, Collinson N, Aegerter J, Venkatesh D, Russell DJF, James J, Reid SM, Banyard AC.   +18 more
europepmc   +1 more source

Injectable Hydrogel with Rapid Coagulation, Low Swelling, and High Burst Pressure Tolerance Properties for Long‐Term Management of Bleeding Wound

Advanced Science, EarlyView.
An injectable PACmC hydrogel with “rigid island‐flexible chain” architecture is developed, featuring low swelling (49.2% within 7 d), strong wet adhesion (46.5 kPa), and high burst pressure (701 mm Hg), which can achieve rapid hemostasis and long‐term sealing in rabbit and porcine models of hepatic and splenic hemorrhage.
Yang Ouyang, Wenfeng Qiu, Weiwen Liang, Xin Zhang, Weijie Liu, Zixin Chen, Yifei Li, Hui Wang, Youchen Tang, Min Li, Rongkang Huang, Zijian Chen, Binghua Ma   +12 more
wiley   +1 more source

Evolutionarily divergent nidovirus with an exceptionally large genome identified in Pacific oysters undergoing mass mortality. [PDF]

Proc Natl Acad Sci U S A
Zhong KX, Chan AM, Miller KM, Saunders R, Suttle CA.   +4 more
europepmc   +1 more source

Mass mortality of pearl oyster (Pinctada fucata (Gould)) in Japan in 2019 and 2020 is caused by an unidentified infectious agent. [PDF]

PeerJ, 2021
Matsuyama T, Miwa S, Mekata T, Matsuura Y, Takano T, Nakayasu C.   +5 more
europepmc   +1 more source

Tyrosinase Driven‐Intracellular Polymerization of a Porphyrin Derivative Induced Immunogenic Death of Melanoma Cells and Strengthened Photodynamic Therapy

Advanced Science, EarlyView.
This study uses tyrosinase, which is highly expressed in melanoma, to drive porphyrins to polymerize and self‐assemble within tumor cells to form retented microstructures. This process induces immunogenic death and activates immune responses (M1 macrophages, dendritic cells, CD8+T cells), turning “cold” tumors into “hot” tumors.
Mian Tang, Junteng Qiu, Yunfeng Lu, Yahui Song, Xinyu Zhou, Tianshun Duan, Xuanqi Peng, Caixia Yin, Cheng Gao, Ruibing Wang   +9 more
wiley   +1 more source

Widespread coral bleaching and mass mortality during the 2023-2024 marine heatwave in Little Cayman. [PDF]

PLoS One
Doherty ML, Johnson JV, Goodbody-Gringley G.   +2 more
europepmc   +1 more source

Integrated Hydrophilic Interdigitated Network for Silicone Rubber via a Gradient Polarity Modification Strategy

Advanced Science, EarlyView.
This work overcomes the long‐standing challenge of hydrophilic modification of silicone rubber via a gradient polarity modification strategy. By constructing a hydrophilic interpenetrating network within cured SR, simultaneous surface‐to‐bulk modification is achieved while enabling monitoring through a Eu3+ complex fluorescent tracer.
Lihui Zhang, Rui Wang, Pingru Su, Yao Kou, Zhengfeng Ma, Hui Tang, Mingying Wang, Lixin Wang, Chunyu Zhou, Shuanhong Ma, Yu Tang, Feng Zhou   +11 more
wiley   +1 more source

Vulnerability of benthic trait diversity across the Mediterranean Sea following mass mortality events. [PDF]

Nat Commun
Carlot J, Galobart C, Gómez-Gras D, Santamaría J, Golo R, Sini M, Cebrian E, Gerovasileiou V, Ponti M, Turicchia E, Comeau S, Rilov G, Tamburello L, Pulido Mantas T, Cerrano C, Ledoux JB, Gattuso JP, Ramirez-Calero S, Millan L, Montefalcone M, Katsanevakis S, Bensoussan N, Garrabou J, Teixidó N.   +23 more
europepmc   +1 more source