Results 91 to 100 of about 8,115,237 (389)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

r.randomwalk v1, a multi-functional conceptual tool for mass movement routing

, 2015
. We introduce r.randomwalk, a flexible and multi-functional open-source tool for backward and forward analyses of mass movement propagation. r.randomwalk builds on GRASS GIS (Geographic Resources Analysis Support System – Geographic Information System),
M. Mergili, Julia Krenn, Hone‐Jay Chu
semanticscholar   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Detailed geomorphology of debris avalanches of El Estribo volcanic complex (Central Mexico)

Journal of Maps, 2020
The El Estribo Volcanic Complex, located to the south of Pátzcuaro Lake (Central Mexico), forms an elevation based on a shield volcano crowned by a cinder cone.
Gemma Gómez-Castillo, Manuel E. Mendoza, José Luis Macías, Nicolás Vargas-Ramírez   +3 more
doaj   +1 more source

Beyond Silence, Towards Refusal: The Epistemic Possibilities of #MeToo [PDF]

, 2019
There are many ways to understand the meanings of the #MeToo movement. Analyses of its significance have proliferated in popular media; some academic analyses have also recently appeared. Commentary on the philosophical and epistemic significance of the #
Miller, Sarah
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Computing Geographical Networks Generated by Air-Mass Movement. [PDF]

Geohealth, 2023
Richard H, Martinetti D, Lercier D, Fouillat Y, Hadi B, Elkahky M, Ding J, Michel L, Morris CE, Berthier K, Maupas F, Soubeyrand S.   +11 more
europepmc   +1 more source

Ornamented intabulations and derived fantasias: parody, imitatio, and genre in Vincenzo Galilei’s lute arrangments of Alessandro Striggios “Nasce la pena mia” [PDF]

, 2011
Jean-Michel Vaccaro in 1981 proposed a four-fold classification of sixteenth-century pieces for solo lute, ordered by the degree to which the composer is constrained by fidelity to a pre-existent model, usually a polyphonic vocal work such as a chanson ...
Argondizza, Peter
core  

The Code of Protest. Images of Peace in the West German Peace Movements, 1945-1990 [PDF]

, 2008
The article examines posters produced by the peace movements in the Federal Republic of Germany during the ColdWar, with an analytical focus on the transformation of the iconography of peace in modernity.
Andreas, Annegret, Armin, Arthur, Axel, Barbara, Belinda, Benjamin, BENJAMIN ZIEMANN, Bernd, Bloch, Bockhofer, Bruno, Christiane, Daniel, Devi, Dietmar, Dietrich, Dora, Ernst, Etzemüller, Frank, Föllmer, Gerhard, Giugni, Günther, Hans, Hans-Karl, Hans-Martin, Hans-Martin, Harald, Heinrich, Herfried, Hildburg, Holger, Hämmerle, Jan, Jens, Jeremi, Jessica, John, Jost, Jost, Jürgens-Kirchhoff, Karl, Kaulbach, Mary, Michael, Michael, Neumann, Niklas, Niklas, Niklas, Niklas, Norbert, Oppenheimer, Paul, Peter, Reiner, Reinhart, Schneider, Sebald, Siegmar, Stefan, Stefan, Stoehr, Thomas, Thompson, Thorsten, Ulrich, Ute, Vittorio, Weart, Werner, Wilfried, Wittner, Ziemann   +76 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source