Huntington's disease is a multi-system disorder. [PDF]
, 2015 Huntingtons disease (HD) is one of the most common non-curable rare diseases and is characterized by choreic movements, psychiatric symptoms, and slowly progressive dementia.
Mielcarek, M
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Gravitational settling in pulsating subdwarf B stars and their progenitors [PDF]
, 2009 Diffusion of atoms can be important during quiescent phases of stellar evolution. Particularly in the very thin inert envelopes of subdwarf B stars, diffusive movements will considerably change the envelope structure and the surface abundances on a short
A. A. Thoul +71 more
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In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Estimation of magnitudes of debris flows in selected torrential watersheds in Slovenia
Acta Geographica Slovenica, 2006 In this paper the application of different methods for estimation of magnitudes of rainfall-induced debris flows in 18 torrents in the Upper Sava River valley, NW Slovenia, and in 2 torrents in Pohorje, N Slovenia is described. Additional verification of
Jošt Sodnik, Matjaž Mikoš
doaj +1 more source
Neotectonics and inferred movements in Canada [PDF]
Bulletin of the Geological Society of Finland, 1988 Neotectonic movements in Canada are due to a variety of causes. Within the Canadian Shield (craton) postglacial rebound appears to be the main contributor.
H.S. Hasegawa
doaj +1 more source
Социальные (исторические) движения в контексте социологических подходов [PDF]
, 2001 The author analyzes social (historical) movements from various sociological points of view, like positivist, behaviorist and functional ones. There are also discussed the resource mobilization concept and the radical-class approach to the mass movements.
Гавриленко, И.
core
Exploding iconography: The Mindbomb Project [PDF]
, 2006 The Mindbomb project was started by a group of young artists, journalists and writers, rich in creative resources. Together they created the social poster.
Mercea, D.
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Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Will present day glacier retreat increase volcanic activity? Stress induced by recent glacier retreat and its effect on magmatism at the Vatnajokull ice cap, Iceland [PDF]
, 2008 Global warming causes retreat of ice caps and ice sheets. Can melting glaciers trigger increased volcanic activity? Since 1890 the largest ice cap of Iceland, Vatnajokull, with an area of similar to 8000 km(2), has been continuously retreating losing ...
Allen +23 more
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