Results 111 to 120 of about 883,360 (293)
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
A Novel Quantum Gravity Approach
Reports in Advances of Physical SciencesWe propose a candidate theory of quantum gravity founded on the entropic projection of a complex operator defined in a Diagram Hilbert Space. This operator unifies mass–energy and charge within a single microscopic entity whose spectral structure encodes
Borros Arneth
doaj +1 more source
Dark Matter characterization at the LHC in the Effective Field Theory approach
Journal of High Energy Physics, 2017 We have studied the complete set of dimension 5 and dimension 6 effective operators involving the interaction of scalar, fermion and vector Dark Matter (DM) with SM quarks and gluons, to explore the possibility to distinguish these operators and ...
Alexander Belyaev +3 more
doaj +1 more source
Light-meson masses in an unquenched quark model
, 2017 We perform a coupled-channels calculation of the masses of light mesons with the quantum numbers $IJ^{P=-}$, $(I,J)=0,1$, by including $q\bar{q}$ and $(q\bar{q})^2$ components in a nonrelativistic chiral quark model.
Chen, Xiaoyun +3 more
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Higgs-portal spin-1 dark matter with parity-violating interaction
Journal of High Energy PhysicsWe introduce the spin-1 U(1) X gauged field X with Z 2 odd dark parity to evade the current strong constraints on kinetic mixing. Then, X becomes stable and a candidate for the dark matter. The lowest mass dimension of interaction is six, and the type is
Kimiko Yamashita
doaj +1 more source
Systematic SO(10) operator analysis for fermion masses
Physical Review D, 1994 65 pages, 22 figures or complete manuscript available by mail.
Anderson, G. +4 more
openaire +3 more sources
Scalar Field Theory in the AdS/CFT Correspondence Revisited
, 2000 We consider the role of boundary conditions in the $AdS_{d+1}/CFT_{d}$ correspondence for the scalar field theory. Also a careful analysis of some limiting cases is presented.
Arutyunov +21 more
core +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source