Modulating pressure in the Orbitrap improves sensitivity and mass resolution in charge detection mass spectrometry [PDF]
Nature CommunicationsNative mass spectrometry has become a key method for studying macromolecular assemblies, providing insights into structures, stoichiometries, and binding interactions. A key aspect for the transmission of electrospray-generated bioparticles into the mass
Eduard H.T.M. Ebberink +8 more
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MIMI: Molecular Isotope Mass Identifier for stable isotope-labeled Fourier transform ultra-high mass resolution data analysis [PDF]
BMC BioinformaticsBackground Ultra High Resolution (UHR) mass spectrometry systems with Fourier Transform Ion Cyclotron Resonance (FT-ICR) are often used to analyze the composition of complex mixtures of naturally-occurring or isotopically-enriched small molecules, such ...
Nabil Rahiman +3 more
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Low‐Cost, Compact Quadrupole Mass Filters with Unity Mass Resolution via Ceramic Resin Vat Photopolymerization [PDF]
Advanced ScienceThis study reports novel, compact, and additively manufactured quadrupole mass filters (QMFs) with adequate filtering performance for practical mass spectrometry applications.
Colin C. Eckhoff +4 more
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Current Progress in Femtosecond Laser Ablation/Ionisation Time-of-Flight Mass Spectrometry
Applied Sciences, 2021 The last decade witnessed considerable progress in the development of laser ablation/ionisation time-of-flight mass spectrometry (LI-TOFMS). The improvement of both the laser ablation ion sources employing femtosecond lasers and the method of ion ...
Marek Tulej +7 more
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Machine Learning-Assisted Recognition of Environmental Sulfur-Containing Chemicals in Nontargeted Mass Spectrometry Analysis of Inadequate Mass Resolution [PDF]
ACS Environmental AuBrian Low +3 more
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Nature Communications, 2021 The trans-Golgi network (TGN) serves as a platform to sort and transport proteins to their final destinations. Here the authors show that the TGN of Arabidopsis consists of spatially and temporally distinct subregions and propose that these zones may ...
Yutaro Shimizu +12 more
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Simulation of a Miniature Linear Ion Trap with Half-Round Rod Electrodes
Micromachines, 2022 The miniaturization of ion trap mass analyzers is an important direction in the development of mass spectrometers. In this work, we proposed two models of miniaturized HreLIT with a field radius of about 2 mm based on the existing research on ...
Xichi Lu +7 more
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Molecules, 2022 In this article, we have presented the development and validation of a rapid and sensitive reversed-phase liquid chromatography with tandem mass spectrometry (LC-MS/MS) method for the determination of vincristine (VCR) in patient serum samples ...
Kamil Jurowski +8 more
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Effects of excessive alcohol drinking on nicotine biotransformation in rats
Scientific Reports, 2022 Alcohol and nicotine (tobacco smoke) are often used together, and taking both addictive substances is associated with an increased risk of certain diseases. It is extremely important to understand the pharmacodynamic and pharmacokinetic mechanisms of the
Joanna Kasprzyk +4 more
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Antioxidants, 2023 Hepatocellular damage by the harmful effects of xenobiotics, which increase the production of free radicals, is a widespread phenomenon. The extract from the leaves of Cynara scolymus L.
Ewa Florek +11 more
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