Results 51 to 60 of about 975,461 (302)
A new, high-resolution global mass coral bleaching database. [PDF]
PLoS ONE, 2017 Episodes of mass coral bleaching have been reported in recent decades and have raised concerns about the future of coral reefs on a warming planet. Despite the efforts to enhance and coordinate coral reef monitoring within and across countries, our ...
Simon D Donner +2 more
doaj +1 more source
, 2019 Mass spectrometry imaging (MSI) and histology are complementary analytical tools. Integration of the two imaging modalities can enhance the spatial resolution of the MSI beyond its experimental limits.
Heeren, Ron M. A. +4 more
core +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
MoleculesPlatelet extracellular vesicles (PEVs) are emerging as key biomarkers in diabetes mellitus (DM), reflecting altered platelet function and coagulation pathways.
Joanna Kasprzyk-Pochopień +5 more
doaj +1 more source
DESIR high resolution separator at GANIL, France [PDF]
Nuclear Technology and Radiation Protection, 2012 A high-resolution separator for the SPIRAL2/DESIR project at GANIL has been designed. The extracted isotopes from SPIRAL2 will be transported to and cooled in a RFQ cooler yielding beams with very low transverse emittance and energy spread.
Toprek Dragan, Kurtukian-Nieto Teresa
doaj +1 more source
Improvement in the Mass Resolution of Single Particle Mass Spectrometry Using Delayed Ion Extraction
, 2018 A specific delayed ion extraction (DIE) technique, which combines a standard rectangular extraction pulse with an exponential pulse, was introduced for a single particle mass spectrometry (SPMS) instrument, and it can focus ions in a wide mass range and ...
Xu, Li +7 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
, 2022 Omics-based technologies have enabled comprehensive characterization of our exposure to environmental chemicals (exposome) as well as assessment of the corresponding biological responses at the molecular level (e.g., metabolome, lipidome, proteome, and ...
Joseph, Okeme +21 more
core +1 more source