Results 201 to 210 of about 943,382 (267)

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source
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MASS SCREENING FOR GLAUCOMA

Journal of the American Medical Association, 1951
There is general agreement among all ophthalmologists that the most important factor in the management of chronic simple glaucoma is early detection. Review of the literature on glaucoma reveals no extensive study concerning the incidence of this disease in a cross section of a normal population.
S S, BRAV, H P, KIRBER
openaire   +2 more sources

Mass Screening for Diabetes

Archives of Environmental Health: An International Journal, 1970
Dexfrostix were used to estimate blood sugar levels In three different mass screening applications. Close interpolation of values was not attempted, only the closest value on the manufacturer’s color chart. “Positives” were qualified with additional testing methods.
C H, Rushmore, T A, Mabel
openaire   +2 more sources

Individual and Mass Screening

2012
Screening for prostate cancer is one of the main current health issues nowadays. As prostate cancer is the most frequently diagnosed cancer affecting over 10% of men in the Western world, early detection by mass screening or by individual approaches has to be considered in order to reduce disease-specific morbidity and mortality.
Bangma, Chris H.   +2 more
openaire   +2 more sources

Mammography in mass screening

European Journal of Cancer (1965), 1979
Abstract The statement on X-ray mammography in screening for breast cancer which was released by the National Cancer Institute in August 1976 is critically evaluated. The considerations which have led to the discontinuation of the use of mammography for screening of healthy women under 50 yr of age in the U.S. are analysed.
openaire   +3 more sources

Mass screening electroencephalography

Brain and Development, 1981
From 1971 to 1978, 5,202 schoolchildren from the first to the 9th grade underwent mass screening EEG. Paroxysmal discharges were recognized in 1.7%. Focal paroxysmal discharges appeared most frequently and the temporal, occipital, and central areas were the most common sites.
openaire   +2 more sources

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