Results 121 to 130 of about 5,476,582 (407)
Background Data from biological samples and medical evaluations plays an essential part in clinical decision making. This data is equally important in clinical studies and it is critical to have an infrastructure that ensures that its quality is ...
Jonatan Eriksson+10 more
doaj +1 more source
Variational autoencoders for tissue heterogeneity exploration from (almost) no preprocessed mass spectrometry imaging data [PDF]
The paper presents the application of Variational Autoencoders (VAE) for data dimensionality reduction and explorative analysis of mass spectrometry imaging data (MSI). The results confirm that VAEs are capable of detecting the patterns associated with the different tissue sub-types with performance than standard approaches.
arxiv
Application of tandem two-dimensional mass spectrometry for top-down deep sequencing of calmodulin [PDF]
Two-dimensional mass spectrometry (2DMS) involves simultaneous acquisition of the fragmentation patterns of all the analytes in a mixture by correlating their precursor and fragment ions by modulating precursor ions systematically through a fragmentation
Barrow, Mark P.+5 more
core +1 more source
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit+19 more
wiley +1 more source
Panax ginseng, a venerable herb in traditional Chinese medicine, boasts a rich history of usage in the treatment of dementia, particularly in its various manifestations.
Yu-ting FAN+5 more
doaj +1 more source
Pitfall in the high-throughput quantification of whole blood cyclosporin A using liquid chromatography-tandem mass spectrometry [PDF]
In a growing number of laboratories the technique of liquid chromatography-tandem mass spectrometry is used for the quantification of cyclosporin A in whole blood, employing cyclosporin D as the internal standard. Cyclosporin A is extensively metabolized
Spöhrer, Ute, Vogeser, Michael
core +1 more source
Ambient Ionization Mass Spectrometry: Recent Developments and Applications.
The early 2000s brought a new age in the field of mass spectrometry (MS) with the introduction of ambient ionization MS techniques. As defined by one of its early visionaries, Prof. R.
Clara L. Feider+3 more
semanticscholar +1 more source
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez+17 more
wiley +1 more source
On-line Analysis of the Electrochemical Oxidation of Dopamine in High Concentration Phosphate Buffer Solution by Electrochemical Mass Spectrometry [PDF]
Electrochemical mass spectrometry is an important technique for studying the mechanism of electrochemical reactions. Mass spectrometry has the advantages of high detection sensitivity, high detection throughput and high specificity, which enables ...
LIN Jia-mei+6 more
doaj +1 more source
A Cyclic Ion Mobility-Mass Spectrometry System.
Improvements in the performance and availability of commercial instrumentation have made ion mobility-mass spectrometry (IM-MS) an increasingly popular approach for the structural analysis of ionic species as well as for separation of complex mixtures ...
K. Giles+6 more
semanticscholar +1 more source