Results 141 to 150 of about 5,622,516 (403)
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Advanced undergraduate experiments in vacuum physics and mass spectrometry [PDF]
, 1980 A comprehensive high‐vacuum system has been set up and operated in an advanced undergraduate laboratory for students majoring in physics and microelectronics.
Golecki, I., Rossel, J.
core
Advanced Biology, EarlyView.The review provides a critical up‐to‐date overview of the current landscape of human in vitro models for fatty liver disease, including spheroids, organoids, organ‐on‐a‐chip systems, bioprinted liver constructs and precision‐cut liver slices. Their utility for faithfully modeling different stages of MASLD and MASH are evaluated and their compatibility ...
Sonia Youhanna +6 more
wiley +1 more source
Advanced ScienceBioenergetic therapy is emerging as a promising therapeutic approach. However, its therapeutic effectiveness is restricted by metabolic plasticity, as tumor cells switch metabolic phenotypes between glycolysis and oxidative phosphorylation (OXPHOS) to ...
Xiangjun Wei +7 more
doaj +1 more source
Molecular characterization of S‐ and N‐containing organic constituents in ambient aerosols by negative ion mode high‐resolution Nanospray Desorption Electrospray Ionization Mass Spectrometry: CalNex 2010 field study [PDF]
, 2014 Rachel E. O’Brien +5 more
openalex +1 more source
A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study
Advanced Biology, EarlyView.Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers +10 more
wiley +1 more source
Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging of Metabolites during Sorghum Germination [PDF]
, 2020 Lucia Montini +5 more
openalex +1 more source
Analyses of moisture in polymers and composites [PDF]
A suitable method for the direct measurement of moisture concentrations after humidity/thermal exposure on state of the art epoxy and polyimide resins and their graphite and glass fiber reinforcements was investigated.
Ryan, L. E., Vaughan, R. W.
core +1 more source
High‐Temperature Oxidation of the CrFeNi Medium‐Entropy Alloy
Advanced Engineering Materials, EarlyView.The oxidation behavior of equiatomic CrFeNi MEA is a key issue that determines this material's suitability for high‐temperature application. The understanding of long‐term behavior is even more crucial than short‐term corrosion effects. The alloy is exposed to synthetic air at 1000, 1050, and 1100 °C for 24, 100, and 1000 h and systematically compared ...
Anna Maria Manzoni +5 more
wiley +1 more source