Results 161 to 170 of about 5,476,582 (407)

Mass spectrometry of RNA

Trends in Biochemical Sciences, 2006
A complex population of non-coding RNAs is present in higher organisms. These RNAs have a multitude of functions and execute control over gene expression through various, often poorly understood, mechanisms. At present, the identification and analysis of functional regulatory RNAs and disparate ribonucleoprotein complexes remain an experimental ...
Thomas, B, Akoulitchev, A
openaire   +4 more sources

Mass spectrometry-based metabolomics: a guide for annotation, quantification and best reporting practices

Nature Methods, 2021
S. Alseekh, A. Aharoni, Y. Brotman, K. Contrepois, J. D’Auria, Jan Ewald, Jennifer C Ewald, P. Fraser, Patrick Giavalisco, R. Hall, Matthias Heinemann, H. Link, Jie Luo, S. Neumann, J. Nielsen, Leonardo Perez de Souza, K. Saito, U. Sauer, F. Schroeder, S. Schuster, G. Siuzdak, A. Skirycz, L. Sumner, M. Snyder, Huiru Tang, Takayuki Tohge, Yulan Wang, Weiwei Wen, Si Wu, Guowang Xu, Nicola Zamboni, A. Fernie   +31 more
semanticscholar   +1 more source

Mass Spectrometry Approaches to Glycomic and Glycoproteomic Analyses.

Chemical Reviews, 2018
Glycomic and glycoproteomic analyses involve the characterization of oligosaccharides (glycans) conjugated to proteins. Glycans are produced through a complicated nontemplate driven process involving the competition of enzymes that extend the nascent ...
L. R. Ruhaak, Gege Xu, Qiongyu Li, E. Goonatilleke, C. Lebrilla   +4 more
semanticscholar   +1 more source

Exploring the causal relationship between glutamine metabolism and leukemia risk: a Mendelian randomization and LC-MS/MS analysis

Frontiers in Immunology
ObjectiveThis investigation sought to delineate the causal nexus between plasma glutamine concentrations and leukemia susceptibility utilizing bidirectional Mendelian Randomization (MR) analysis and to elucidate the metabolic ramifications of ...
Na Li, Na Li, Tianyi Wang, Huiying Zhang, Huiying Zhang, Huiying Zhang, Xiao Li, Haochen Bai, Ning Lu, Kaizhi Lu, Kaizhi Lu   +10 more
doaj   +1 more source

Calcium modulating ligand confers risk for Parkinson's disease and impacts lysosomes

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Objective Several genetic loci known to confer risk for Parkinson's disease (PD) function in lysosomal pathways. We systematically screened common variants linked to PD risk by genome‐wide association studies (GWAS) for impact on cerebrospinal fluid (CSF) proteins reflecting lysosomal function.
Hanwen Zhang, Daniel Kargilis, Thomas Tropea, John Robinson, Junchao Shen, Eliza M. Brody, Ann Brinkmalm, Simon Sjödin, Adama J. Berndt, Marc Carceles‐Cordon, EunRan Suh, Vivianna M. Van Deerlin, Kaj Blennow, Daniel Weintraub, Edward B. Lee, Henrik Zetterberg, Alice S. Chen‐Plotkin   +16 more
wiley   +1 more source

Identification of mono- and dihydroxy bile acids in human feces by gas-liquid chromatography and mass spectrometry

Journal of Lipid Research, 1966
The mono- and disubstituted cholanoic acids present in human feces have been investigated. Extracts of feces were fractionated on silicic acid column and individual bile acids were isolated by preparative thin-layer chromatography. The isolated compounds
Peter Eneroth, Bruce Gordon, Ragnar Ryhage, Jan Sjövall   +3 more
doaj  

Boosting Energy Deprivation by Synchronous Interventions of Glycolysis and Oxidative Phosphorylation for Bioenergetic Therapy Synergetic with Chemodynamic/Photothermal Therapy

Advanced Science
Bioenergetic therapy is emerging as a promising therapeutic approach. However, its therapeutic effectiveness is restricted by metabolic plasticity, as tumor cells switch metabolic phenotypes between glycolysis and oxidative phosphorylation (OXPHOS) to ...
Xiangjun Wei, Renlu Han, Yun Gao, Pengxin Song, Zhen Guo, Yafei Hou, Jiancheng Yu, Keqi Tang   +7 more
doaj   +1 more source

Mass spectrometry-based characterization of the virion proteome, phosphoproteome, and associated kinase activity of human cytomegalovirus [PDF]

, 2020
Bruley, C., Buscher, N., Coute, Y., De Andrea, M., Hahn, F., Hesse, A. -M., Kraut, A., Marschall, M., Plachter, B., Wangen, C., Zimmermann, C.   +10 more
core   +1 more source

High-accuracy Penning trap mass measurements with stored and cooled exotic ions

, 2009
The technique of Penning trap mass spectrometry is briefly reviewed particularly in view of precision experiments on unstable nuclei, performed at different facilities worldwide.
Blaum K, Blaum K, Bollen G, Böhm S, Crespo López-Urrutia J R, G Werth, K Blaum, Kinoshita T, Major F G, Nagy Sz, Otten E W, Schabinger B, Sz Nagy, Weber C, Wicht A   +14 more
core   +1 more source

Evidence of blood–brain barrier dysfunction and CSF immunoglobulin synthesis in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Objectives This study sought to evaluate proteomic, metabolomic, and immune signatures in the cerebrospinal fluid of individuals with Down Syndrome Regression Disorder (DSRD). Methods A prospective case–control study comparing proteomic, metabolomic, and immune profiles in individuals with DSRD was performed.
Jonathan D. Santoro, Neetha Paul Eduthan, Mellad M. Khoshnood, Saba Jafarpour, Natalie K. Boyd, Benjamin N. Vogel, Lina Nguyen, Lilia Kazerooni, Eleanor Britton, Hannah R. Lyford, Matthew D. Galbraith, Angela L. Rachubinski, Joaquin M. Espinosa   +12 more
wiley   +1 more source