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Mass Spectrometry

2012
Mass spectrometry has evolved to become the biggest (in market share and total expenditure) analytical technology. It is also the analytical instrumentation sector with the biggest annual increase, thus signifying its importance and value. Mass spectrometry has become the method of choice because it offers unique characteristics not provided by other ...
Kaklamanos, G.   +2 more
openaire   +2 more sources

Mass Spectrometry

2009
For twenty years or so now, mass spectrometry has been used to get exact measurements of the mass of biological molecules such as proteins, nucleic acids,oligosaccharides, and so on. Over the past ten years, this technology has followed the trend toward miniaturisation and the samples required can be much smaller.
Pflieger, D., Forest, E., Vinh, J.
openaire   +2 more sources

Electrospray ionization for mass spectrometry of large biomolecules.

Science, 1989
Electrospray ionization has recently emerged as a powerful technique for producing intact ions in vacuo from large and complex species in solution. To an extent greater than has previously been possible with the more familiar "soft" ionization methods ...
J. Fenn   +4 more
semanticscholar   +1 more source

Anatomy and evolution of database search engines-a central component of mass spectrometry based proteomic workflows.

Mass spectrometry reviews (Print), 2020
Sequence database search engines are bioinformatics algorithms that identify peptides from tandem mass spectra using a reference protein sequence database.
K. Verheggen   +5 more
semanticscholar   +1 more source

Identifying small molecules via high resolution mass spectrometry: communicating confidence.

Environmental Science and Technology, 2014
T increased availability of high resolution mass spectrometry (HR-MS) in chemical analysis has dramatically improved the detection and identification of compounds in environmental (and other) samples.
Emma L. Schymanski   +6 more
semanticscholar   +1 more source

Glycomics and Mass Spectrometry

Current Pharmaceutical Design, 2005
Proteomics is closely associated with the modifications of the gene product such as the post-translational events that yield functionally active gene products. Among these, glycosylation represents a critically important post-translational modification and is a target for proteomic research.
Morelle, Willy, Michalski, Jean-Claude
openaire   +4 more sources

Mass Spectrometry and Tandem Mass Spectrometry of Citrus Limonoids [PDF]

open access: possibleAnalytical Chemistry, 2003
Methods for atmospheric pressure chemical ionization tandem mass spectrometry (APCI-MS/MS) of citrus limonoid aglycones and electrospray ionization tandem mass spectrometry (ESI-MS/MS) of limonoid glucosides are reported. The fragmentation patterns of four citrus limonoid aglycones (limonin, nomilin, obacunone, and deacetylnomilin) and six limonoid ...
Steven J. Schwartz, Qingguo Tian
openaire   +2 more sources

FIELDABLE MASS SPECTROMETRY FOR FORENSIC SCIENCE, HOMELAND SECURITY, AND DEFENSE APPLICATIONS.

Mass spectrometry reviews (Print), 2020
Mass spectrometry is commonly used in forensic chemistry laboratories for sensitive, definitive analysis. There have been significant efforts to bring mass spectrometry analysis on-site through the development of ruggedized, fieldable instruments ...
K. Evans-Nguyen   +4 more
semanticscholar   +1 more source

Accelerator mass spectrometry

Analytical Chemistry, 1995
Accelerator mass spectroscopy (AMS) can be used for efficient detection of long-lived isotopes at part-per-quadrillion sensitivities with good precision. In this article we present an overview of AMS and its recent use in archaeology, geochemistry and biomolecular tracing.
John S. Vogel   +3 more
openaire   +2 more sources

Mass Spectrometry for the Masses

Journal of Chemical Education, 2004
Students in an introductory or nonmajors chemistry course have little to no background in scientific instrumentation. However, advanced instrumentation can be employed to further students' understanding of basic chemistry and scientific methods. In this article, we describe an experiment for an introductory chemistry course that incorporates the use of
Michael J. Samide   +2 more
openaire   +2 more sources

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