The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity
FEBS Open Bio, EarlyView.We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda +9 more
wiley +1 more source
Predicting individual perceptual scent impression from imbalanced dataset using mass spectrum of odorant molecules. [PDF]
Sci Rep, 2022 Debnath T, Nakamoto T.
europepmc +1 more source
Zeitschrift für Physik C: Particles and Fields, 1989 We present a detailed study of the mass spectrum of SQCD in the vector, axial vector, Goldstone and flavour-singlet channels in the caseN c =M F by means of SVZ sum rules in their finite energy version.
openaire +2 more sources
The quest for the neutrino mass spectrum [PDF]
, 2000 This article provides a (semi-)popular introduction to the phenomenology of neutrino masses.Comment: 19 pages, 6 ...
Klapdor-Kleingrothaus, H. V., Päs, H.
core +2 more sources
Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective [18F]EKZ‐001 is a positron emission tomography (PET) tracer targeting histone deacetylase 6 (HDAC6), an enzyme responsible for intracellular transport and clearance of misfolded proteins. HDAC6 modulation is a promising treatment strategy in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Greet Vanderlinden +15 more
wiley +1 more source
Pathway Analyses of Inherited Neuropathies Identify Putative Common Mechanisms of Axon Degeneration
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Inherited neuropathies (IN) are associated with over 100 different genetic mutations presenting with a variety of phenotypes. This complexity suggests multiple pathways may converge onto a limited number of downstream pathways to effect axonal injury.
Christopher R. Cashman +2 more
wiley +1 more source
Erratum: Metastable Transitions in the Mass Spectrum of Benzene [PDF]
, 1966 Keith R. Jennings
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Arthritis Care &Research, EarlyView.Objective We aimed to assess whether high‐sensitivity C‐reactive protein (hsCRP) levels could predict the development of psoriatic arthritis (PsA) in patients with psoriasis. Methods We analyzed data from a prospective cohort of patients with psoriasis without PsA at enrollment.
Lihi Eder +5 more
wiley +1 more source
Probabilistic framework for integration of mass spectrum and retention time information in small molecule identification. [PDF]
Bioinformatics, 2021 Bach E, Rogers S, Williamson J, Rousu J.
europepmc +1 more source
The Mass Spectrum of Interstellar Clouds and the Assumption of Total Coalescence [PDF]
, 1972 L. G. Taff, M. P. Savedoff
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