Results 231 to 240 of about 2,237,751 (385)

Targeting IGF1R Overcomes Armored and Cold Tumor Microenvironment and Boosts Immune Checkpoint Blockade in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
IGF1R is highly expressed in the armored & cold tumors, and collagen mediates IGF1R at the transcriptional and post‐translational levels to promote TNBC cell invasion and immune escape and to stabilize its own structure by interacting with the collagen receptor DDR1.
Mengyun Wan   +8 more
wiley   +1 more source

Evidence of Disrupted Hippocampal Gray- and White-Matter Development in Adolescent Anxiety Disorders, Independent From Early-Life Stress. [PDF]

open access: yesHippocampus
Pedroza-Sotelo K   +10 more
europepmc   +1 more source

RPL6 Interacts with HMGCS1 to Stabilize HIF‐1α by Promoting Cholesterol Production in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
The study found that RPL6 is frequently upregulated in HCC tissues with extrahepatic metastasis. Elevated RPL6 bound to and increased the stability of HMGCS1 mRNA, thereby enhancing intracellular cholesterol levels. Subsequently, increased cholesterol promotes cancer metastasis in HCC by stabilizing HIF‐1α protein.
Minli Yang   +15 more
wiley   +1 more source

Jobs in Springfield, Massachusetts: understanding and remedying the causes of low resident employment rates [PDF]

open access: yes
As part of the Federal Reserve Bank of Boston's commitment to supporting efforts to revitalize the economy of Springfield, Massachusetts, this paper explores the causes of and potential remedies for the city's low resident employment rates. When compared
Ana Patricia Muñoz with Lynn Browne   +6 more
core  

ε‐Poly‐L‐lysine‐graft‐oligo(3‐hexylthiophene) Copolymers as Antibacterial and Biodegradable Polymer Electronics

open access: yesAdvanced Science, EarlyView.
ε‐Poly‐L‐lysine‐graft‐oligo(3‐hexylthiophene) (EPL‐g‐O3HT) copolymers are engineered as biodegradable and antibacterial materials for transient electronics. EPL‐g‐O3HT exhibits tunable conductivity, controlled enzymatic degradability, good biocompatibility, and potent antibacterial activity. They are demonstrated in electromyography sensors and organic
Xin Sun   +9 more
wiley   +1 more source

The normalizing properties of intracranial volume across race and sex. [PDF]

open access: yesBrain Commun
Liu P   +14 more
europepmc   +1 more source

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