Results 231 to 240 of about 1,737,375 (313)

KK2DP7 Stimulates CD11b+ Cell Populations in the Spleen to Elicit Trained Immunity for Anti‐Tumor Therapy

open access: yesAdvanced Science, EarlyView.
This study introduces KK2DP7, a dendrimer‐structured peptide adjuvant, as a tool to decode trained immunity's role in antitumor therapy. Splenic CD11b+ cells mediate tumor suppression via TLR2‐IRF7 activation and epigenetic reprogramming, validated by adoptive transfer experiments.
Rui Zhang   +5 more
wiley   +1 more source

The State of High‐Resolution Imaging of the Human Inner Ear: A Look Into the Black Box

open access: yesAdvanced Science, EarlyView.
High‐resolution imaging of the cochlea is challenged by numerous unique aspects of this organ, where sensorineural cells, crucial for hearing, are too small for conventional modalities like magnetic resonance imaging and computed tomography. This article reviews current imaging techniques, emerging technologies, and innovations aimed at improving ...
Shelley Batts   +3 more
wiley   +1 more source

Continuous Adductor Canal Block Compared to Epidural Anesthesia for Total Knee Arthroplasty [Response to Letter]

open access: yesJournal of Pain Research
Isaac G Freedman,1 Jinlei Li2 1Department of Anesthesiology, Critical Care & Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; 2Department of Anesthesiology, Yale School of Medicine, New Haven, CT ...
Freedman IG, Li J
doaj  

Explainable Deep Multilevel Attention Learning for Predicting Protein Carbonylation Sites

open access: yesAdvanced Science, EarlyView.
Selective carbonylation sites (SCANS) are conceptualized, designed, evaluated, and released. SCANS captures segment‐level, protein‐level, and residue embeddings features. It utilizes elaborate loss function to penalize cross‐predictions at the residue level.
Jian Zhang   +6 more
wiley   +1 more source

Wonders of Harbor and Grey Seal Whiskers: Morphology, Natural Frequencies, and 3D Modeling

open access: yesAdvanced Science, EarlyView.
Seals detect prey by sensing vortices using whiskers. How whisker morphologies and locations respond to hydrodynamic signals across various frequencies remains unclear. This study measures whiskers’ natural frequencies and morphologies and maps them to whisker locations on the muzzle, providing insights into how seals interpret hydrodynamic signals ...
Xingwen Zheng   +4 more
wiley   +1 more source

Low‐Frequency Noise Spectroscopy for Navigating Geometrically Varying Strain Effects in HfO2 Ferroelectric FETs

open access: yesAdvanced Science, EarlyView.
This study investigates the material and geometrically varying strain effects on HfO2 ferroelectric FETs (FeFETs). Through noise analysis, the reverse scaling effect is demonstrated due to the strain effects in the FeFET structure. This result indicates the importance of strain engineering in the FeFET for optimized performance.
Ryun‐Han Koo   +10 more
wiley   +1 more source

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