Results 61 to 70 of about 240,909 (351)

Eosinophils‐Induced Lumican Secretion by Synovial Fibroblasts Alleviates Cartilage Degradation via the TGF‐β Pathway Mediated by Anxa1 Binding

Advanced Science, EarlyView.
Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen, Yuwei Zhou, Wenxiu Yuan, Yanjing Ou, Hanyu Lin, Kaixun He, Xueshen Qian, Huachen Chen, Chengchaozi Wang, Jie Lu, Weiping Chen, Dexiong Li, Jiang Chen   +12 more
wiley   +1 more source

“Adjusting internal organs and dredging channelon” electroacupuncture glycolipid metabolism disorders in NAFLD mice by mediating the AMPK/ACC signaling pathway

Diabetology & Metabolic Syndrome
To investigate the effect mechanism of electroacupuncture based on the AMP-activated protein kinase (AMPK) /acetyl-CoA carboxylase (ACC) signaling pathway to improve glycolipid metabolism disorders in db/db mice.
Xinyu Jia, Mengyuan Li, Wen Zhang, Yihui Guo, Fuyu Xue, Shiqi Ma, Shuo Yu, Zhen Zhong, Haipeng Huang   +8 more
doaj   +1 more source

Mapping the mitochondrial landscape in T2DM: key findings from 2003-2023

Frontiers in Endocrinology
BackgoundT2DM, a chronic metabolic disorder, poses a significant threat to global public health. Mitochondria play a crucial role in the pathogenesis of T2DM.
Yi Tan, Mingjun Liu, Xinfeng Zhou, Tianjiao Gao, Jinxu Fang, Sixian Wang, Shaotao Chen   +6 more
doaj   +1 more source

“Olfactory Three-Needle” Enhances Spatial Learning and Memory Ability in SAMP8 Mice

Behavioural Neurology, 2020
As one of the most important therapies in complementary and alternative medicine, acupuncture has been used in the treatment of Alzheimer’s disease (AD).
Yuan Wang, Qiang Wang, Bo Ren, Ting Guo, Jing Qiang, Hui Cao, Yujie Gao, Zhibin Liu, Xinyan Gao, Bing Zhu   +9 more
doaj   +1 more source

Anthocyanins Prevent Mastitis Exacerbation by Inhibiting PANoptosis Activation

Advanced Science, EarlyView.
PANoptosis activation is an effective therapeutic target during mastitis progression, and Gasdermin D activation is key factor contributing to blood milk barrier damage during mastitis, while cyanidin 3‐O‐galactoside can inhibit these targets to exert a protective effect. Therefore, the extraction of key active ingredients from plants for the treatment
Rui Feng, Lin Guo, Fan Wang, Qian Zhang, Guoyan Wang, Hefei Huang, Wei Du, Hong An, Yue Yang, Henghui Miao, Peng Zheng, Tingting Chu, Dengke Zhang, Xiaoxue Yan, Xiaoyu Mi, Qian Ma, Weilin Gao, Yushan Li, Song Li, Yong Zhang, Zhenliang Zhu, Yu Wang, Jun Liu, Xu Liu   +23 more
wiley   +1 more source

Application and Progression of Single-Cell RNA Sequencing in Diabetes Mellitus and Diabetes Complications

Journal of Diabetes Research
Diabetes is a systemic metabolic disorder primarily caused by insulin deficiency and insulin resistance, leading to chronic hyperglycemia. Prolonged diabetes can result in metabolic damage to multiple organs, including the heart, brain, liver, muscles ...
Jiajing Hong, Shiqi Lu, Guohui Shan, Yaoran Yang, Bailin Li, Dongyu Yang   +5 more
doaj   +1 more source

BRUSH MASSAGE [PDF]

The Journal of Nervous and Mental Disease, 1901
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openaire   +2 more sources

Hyperspectral Imaging Techniques for Lyophilization: Advances in Data‐Driven Modeling Strategies and Applications

Advanced Science, EarlyView.
Lyophilization is a key process used in the production of biotherapeutic products. This article reviews and discusses the application of HSI on lyophilization, and the strategies that use the resulting data to build models. It is intended to provide guidance and insights for non‐specialist researchers and engineers into leveraging HSI and the data ...
Huiwen Yu, Prakitr Srisuma, Cedric Devos, Jie Wang, Allan S. Myerson, Richard D. Braatz   +5 more
wiley   +1 more source

Effect of tuina on sleep quality, psychological state and neurotransmitter level in patients with insomnia: a systematic review and meta-analysis

Frontiers in Neurology
BackgroundAbnormal psychological state and neurotransmitter levels are important factors affecting sleep quality. Numerous studies have shown that tuina can improve the symptoms of sleep disorders in patients with insomnia while relieving anxiety and ...
Zhen Wang, Hui Xu, Hui Xu, Zheng Wang, Hang Zhou, Lijuan Zhang, Yu Wang, Miaoxiu Li, Yunfeng Zhou   +8 more
doaj   +1 more source

Massage perceptions and attitudes of undergraduate pre-professional health sciences students: a cross-sectional survey in one U.S. university

BMC Complementary Medicine and Therapies, 2020
Background Attitudes and beliefs about massage therapy have been explored among health professionals and health profession students, but not for undergraduate preprofessional health sciences students.
Niki Munk, Abby Church, Donya Nemati, Samantha Zabel, Amber R. Comer   +4 more
doaj   +1 more source