Results 171 to 180 of about 4,646,931 (348)

Adiabatically steered open quantum systems: Master equation and optimal phase [PDF]

, 2010
J. Salmilehto, Paolo Solinas, Joachim Ankerhold, Mikko Möttönen   +3 more
openalex   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Modeling bursty transcription and splicing with the chemical master equation. [PDF]

Biophys J, 2022
Gorin G, Pachter L.
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Temperature and Pressure Dependence of the Reaction between Ethyl Radical and Molecular Oxygen: Experiments and Master Equation Simulations. [PDF]

J Phys Chem A, 2023
Pekkanen TT, Timonen RS, Ramu EA, Lendvay G, Eskola AJ.   +4 more
europepmc   +1 more source

Dynamics of a narrow-band exciton coupled with optical phonons: A time-convolutionless master-equation approach [PDF]

, 2009
Vincent Pouthier
openalex   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Congestion Transition on Random Walks on Graphs

Entropy
The formation of congestion on an urban road network is a key issue for the development of sustainable mobility in future smart cities. In this work, we propose a reductionist approach by studying the stationary states of a simple transport model using a
Lorenzo Di Meco, Mirko Degli Esposti, Federico Bellisardi, Armando Bazzani   +3 more
doaj   +1 more source

Flare Frequency Distributions Based on a Master Equation [PDF]

, 1998
M. S. Wheatland, S. Glukhov
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source