Results 101 to 110 of about 178,319,880 (288)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Proceedings of the Arizona-Nevada Academy of Science, Volume 19 (1984)

, 1983
TWENTY EIGHTH ANNUAL MEETING / April 7, 1984 / Joint Meeting with the Pacific Division of the American Association for the Advancement of Science / Participating Societies: Arizona Junior Academy of Science, American Water Resources Association ...
Arizona-Nevada Academy of Science
core  

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Proceedings of the Arizona-Nevada Academy of Science, Volume 21 (1986)

, 1986
THIRTIENTH ANNUAL MEETING / April 19, 1986 / Joint Meeting with the Pacific Division of the American Association for the Advancement of Science / Participating Societies: Arizona Junior Academy of Science, American Water Resources Association / Glendale ...
Arizona-Nevada Academy of Science
core  

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Proceedings of the Arizona-Nevada Academy of Science, Volume 15 (1980)

, 1979
Twenty-Fourth Annual Meeting of the Arizona-Nevada Academy of Science and the Fifty-Sixth Annual Meeting Southwestern and Rocky Mountain Division American Association for the Advancement of Science / April 9-12, 1980 / Participating Societies: Arizona ...
Arizona-Nevada Academy of Science
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The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Proceedings of the Arizona-Nevada Academy of Science, Volume 20 (1985)

, 1985
TWENTY NINTH ANNUAL MEETING / April 27, 1985 / Joint Meeting with the Pacific Division of the American Association for the Advancement of Science / Participating Societies: Arizona Junior Academy of Science, American Water Resources Association ...
Arizona-Nevada Academy of Science
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Proceedings of the Arizona-Nevada Academy of Science, Volume 23 (1988)

, 1988
THIRTY-SECOND ANNUAL MEETING / April 16, 1988 / Participating Societies - Arizona Junior Academy of Science, American Water Resources Association, Arizona Hydrological Society / University of Arizona / Tucson, ArizonaThis volume is part of the Arizona ...
Arizona-Nevada Academy of Science
core