Results 171 to 180 of about 1,879,889 (305)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Master's programs in vaccinology in Spain: a nationwide systematic environmental scan and a Delphi-informed core curriculum proposal. [PDF]

Front Public Health
Fernández-Chávez AC, Aranaz Andrés JM, Sánchez-Carmona DL, Hernán-García C, Franco FJ.   +4 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Study on cultivation of master of professional degree in nursing science

Huli yanjiu, 2016
姜敏, 田彦璋, 边疆, 王斌全
doaj  

Master of Health Science/Doctor of Health Science Accelerated Dual-Degree Program Course Catalog [PDF]

, 2006
Nova Southeastern University
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Impact of the Council of State Neurosurgical Societies (CSNS) Fellowship on the Development of Neurosurgical Careers: A Retrospective Study. [PDF]

Cureus
Rawson C, Tenhoeve S, Oladipo O, Carter A, Bauer S, Lucke-Wold B, Benzil D, Adogwa O, Sharma A, Karsy M.   +9 more
europepmc   +1 more source

2006 Commencement - Master of Science Degree in Health Law Celebration Ceremony [PDF]

, 2006
Nova Southeastern University
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Global transcription factors analyses reveal hierarchy and synergism of regulatory networks and master virulence regulators in <i>Pseudomonas aeruginosa</i>. [PDF]

Elife
Huang J, Sun Y, Chen F, Li S, You X, Han L, Li J, He Z, Hua C, Yao C, Li T, Lu B, Chang YF, Deng X.   +13 more
europepmc   +1 more source