Results 151 to 160 of about 1,801,366 (281)

Mechanistic Paths for the Gold(I)‐Catalyzed Heteroannulation of Salicylic Amides With Apolar Alkynes Explored With Density Functional Theory Calculations

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
A manifold of catalytic reaction paths can operate in the Au(I)‐catalyzed heteroannulation of salicylic amides and alkynes. However, a subtle initial nucleophilic advantage of N versus O and a kinetic bottleneck at an advanced stage of the mechanistic machinery seems to suffice for the reaction to run on a single path and with exquisite selectivity. We
Ioannis Stylianakis   +3 more
wiley   +1 more source

Global health education programs: Are we embedding contemporary global health needs into the curriculum of master's programs? [PDF]

open access: yesFront Public Health
Bhullar SS   +5 more
europepmc   +1 more source

Elucidation of the Conformational Rate Processes of the Macrocyclic Lactone (–)‐Nonenolide Through Variable Temperature NMR, Quantum Mechanics, and Molecular Dynamics

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
The conformational rate processes that influence the NMR spectra of the ten‐membered lactone (–)‐nonenolide are elucidated using VT‐NMR, QM calculations and MD simulations. Reorientation of the alkene moiety with respect to the ring is identified as the slow exchange process.
Ingso Limbu   +5 more
wiley   +1 more source

Induction of cytochrome P450 2C9 and P‐glycoprotein activity by antiseizure medications: A systematic review and network meta‐analysis

open access: yesEpileptic Disorders, EarlyView.
Abstract Objectives Antiseizure medications (ASMs) can induce the activity of drug‐metabolizing enzymes and drug transporters, including cytochrome P450 (CYP)2C9 and P‐glycoprotein (P‐gp). Our objective was to comparatively assess the effects of ASMs on exposure to clinical CYP2C9 and P‐gp substrates.
Hagar Cohen   +4 more
wiley   +1 more source

Effects of Day‐Patient Treatment on Eating Disorder Symptoms in Persons With Bulimia Nervosa: A Meta‐Analysis

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Objective Outpatient treatment for bulimia nervosa (BN) often fails to reduce core symptoms like binge eating and purging, while inpatient care is costly and separates patients from their everyday environment. Day‐patient treatment offers a middle ground by providing intensive daytime therapy with the opportunity to apply skills at home.
Anna L. Dieffenbacher   +2 more
wiley   +1 more source

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