Results 41 to 50 of about 2,055,844 (275)

Thirsty country: climate change and drought in Australia [PDF]

, 2015
This report argues that climate change is likely making drought worse in the southeast and southwest of Australia, which are some of our most populous regions. Introduction Drought has deeply affected Australia throughout its history.
Climate Council
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The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Primary School Students’ Relations to Physical Education in Northern Norway: Why Do Some Find the Subject Problematic?

Education Sciences
A global discourse surrounding physical education (PE) is shifting towards a stronger emphasis on inclusive practises, but research shows that some students still find the subject problematic.
Linda Hjemgård Johansen, Tor-Egil Nilsen, Siri Sollied Madsen, Svein-Erik Andreassen   +3 more
doaj   +1 more source

Midwestern Regional Climate Center [PDF]

, 2001
Made available in DSpace on 2016-11-14T22:36:27Z (GMT). No. of bitstreams: 2 ISWSIEM2001-01.pdf: 146176 bytes, checksum: 791a8da476fabb8bec8c3d10ae0a0993 (MD5) license.txt: 3973 bytes, checksum: 6c1c5beee39794d995a5ff442f5bd9ab (MD5) Previous issue ...
Midwestern Regional Climate Center
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IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Predictors of Professional Identity among Early Childhood Teacher Students

Education Sciences
Professional identity has been suggested to be decisive for efficiency and high work quality among the workforces. Central in early childhood teacher education is the development of students to become professional actors in a workplace setting upon ...
Anne Karin Vikstøl Olsen, Ingirid Geirsdatter Heald Kjær, Kristin Severinsen Spieler   +2 more
doaj   +1 more source

Seasonal Climate Forecasts and Risk Management Among Georgia Farmers [PDF]

, 2008
Recent increases in the scientific robustness of seasonal climate forecasts have not led to substantial changes in farmers’ risk management strategies of actors, largely because there is poor integration of scientific forecasting into farmers’ decision ...
Hoogenhoom, G., Broad, K., Breuer, N.E, Paz, J., Ingram, K.T, Roncoli, C., Ingram, K.T., Crane, T.A, Breuer, N.E., Crane, T.A., Broad, K, Roncoli, C, Hoogenhoom, G, Paz, J   +13 more
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Association Between Neurofilament Light Chain and Real‐World Ambulatory Function in Progressive MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurofilament light chain (NfL) is a biomarker of neuroaxonal injury in multiple sclerosis (MS), yet associations with functional outcomes remain unclear. Longitudinal associations between serum NfL (sNfL) and daily step count (STEPS) from wearable devices were assessed in a large international progressive MS cohort.
Gabby B. Joseph, Megan McCune, Riley Bove, Ahmed Abdelhak, Bruce A. C. Cree, Valerie J. Block   +5 more
wiley   +1 more source

Perceived Impacts and Predictors of Cannabis Products Used by Patients with Rheumatologic Conditions in Alberta, Canada: A Multivariable Analysis of Cross‐Sectional Survey Data

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among patients with rheumatologic conditions and their associations with patient factors, patient‐reported perceived side effects, and positive impacts.
Susan Zhang, Samuel A.J. Lowe, Frank Sun, Allyson Jones, Tarek Turk, Joanne Olson, Pauline Paul, Shelby Yamamoto, Linda Kolewaski, Elaine Yacyshyn, Cheryl A. Sadowski   +10 more
wiley   +1 more source

Going for zero: state decarbonisation strategies for prosperity in a zero-emission world [PDF]

, 2015
This paper explains why states should have a decarbonisation strategy and explores some key policy elements. Abstract Across the world, governments at all levels are implementing policies to reduce carbon emissions, address local air pollution, improve
Climate Institute
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