Results 61 to 70 of about 8,831 (219)

Anti‐Inflammatory Effects of Flavonoids in Otitis Media: A Systematic Review of Pre‐Clinical Evidence

open access: yesFood Frontiers, Volume 6, Issue 6, Page 2554-2574, November 2025.
Otitis media (OM) is a middle ear infection driven by chronic inflammation, leading to tissue damage and complications such as cholesteatoma. Flavonoids, a class of polyphenols with anti‐inflammatory properties, suppress key inflammatory mediators, reducing neutrophilic infiltration and mucosal thickening. These findings suggest flavonoids as potential
Madiha Ajaz   +3 more
wiley   +1 more source

Targeting Neutrophil/Eosinophil Extracellular Traps by Aptamer‐Functionalized Nanosheets to Overcome Recalcitrant Inflammatory Disorders

open access: yesAdvanced Science, Volume 12, Issue 38, October 13, 2025.
In this study, C‐TAH, as multifunctional nanosheets, is developed with tannic acid and histone aptamer coverage. C‐TAH displays mild cytotoxicity, robust dsDNA and NETs/EETs binding efficiency, and potent antioxidant and antibacterial ability in vitro. C‐TAH treatment ameliorates dysregulated inflammation and restores hearing function in animal models,
Yongqiang Xiao   +13 more
wiley   +1 more source

Mastoiditis with Streptococcus pneumoniae serotype 19A in one-dose PCV13 vaccinated three-month-old infant

open access: yesHuman Vaccines & Immunotherapeutics, 2019
Pneumococcal conjugate vaccines (PCV) have been widely used in high-income countries for more than a decade, resulting in a dramatic reduction in pneumococcal disease caused by vaccine serotypes.
B. Gülhan   +2 more
doaj   +1 more source

Therapeutic approach to pediatric acute mastoiditis – an update

open access: yesBrazilian Journal of Otorhinolaryngology, 2019
Introduction: Acute mastoiditis remains the most common complication of acute otitis media. It may rarely appear also in cochlear implant patients. However, the treatment recommendations for this disease are not precisely defined or employed, and in the ...
Józef Mierzwiński   +6 more
doaj   +1 more source

A Validation Study of the Paediatric Non‐Urgent Risk Assessment Management and Nurse Escort Assessment (PaNURAMA) Tool for Paediatric Inter‐Hospital Transfers

open access: yesEmergency Medicine Australasia, Volume 37, Issue 4, August 2025.
ABSTRACT Objective Decision support tools improve risk assessment in critical paediatric inter‐hospital transfers (IHT), however, data on non‐critical transfers of unwell children is limited. This study assessed the validity and reliability of a novel risk stratification tool, paediatric non‐urgent risk assessment management and nurse escort assessment
M. Davison   +5 more
wiley   +1 more source

The State of High‐Resolution Imaging of the Human Inner Ear: A Look Into the Black Box

open access: yesAdvanced Science, Volume 12, Issue 28, July 24, 2025.
High‐resolution imaging of the cochlea is challenged by numerous unique aspects of this organ, where sensorineural cells, crucial for hearing, are too small for conventional modalities like magnetic resonance imaging and computed tomography. This article reviews current imaging techniques, emerging technologies, and innovations aimed at improving ...
Shelley Batts   +3 more
wiley   +1 more source

Novel Loss of Function Variant in SOST From Chinese Family Results in Sclerosteosis 1

open access: yesMolecular Genetics &Genomic Medicine, Volume 13, Issue 7, July 2025.
In this study, we present a case study of a proband who displays abnormal facial expressions accompanied by numbness. The results of the brain MRI show thickening of the skull and disappearance of the diplopia signal. The temporal bone CT scan indicates diffuse osteosclerosis affecting the bilateral ossicular chains and internal auditory meatus, as ...
Yufan Guo   +10 more
wiley   +1 more source

Mastoidite e paralisia facial como manifestações iniciais de Granulomatose de Wegener Mastoiditis and facial paralysis as initial manifestations of Wegener's Granulomatosis

open access: yesBrazilian Journal of Otorhinolaryngology, 2012
A Granulomatose de Wegener (GW) é caracterizada por granulomas necrotizantes e vasculite. Sem tratamento a doença tem prognóstico pobre com índice de mortalidade de 90% em 2 anos.
André Souza de Albuquerque Maranhão   +4 more
doaj   +1 more source

Safety and Efficacy of S53P4 Bioactive Glass in Osteomyelitis Management: A Systematic Review and Meta‐Analysis

open access: yesJournal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 113, Issue 6, June 2025.
ABSTRACT Osteomyelitis remains a difficult‐to‐treat bone infection due to its high recurrence risk, complex surgical demands, and rising rates of multidrug‐resistant organisms. While conventional treatments rely heavily on antibiotic‐loaded materials, bioactive glass S53P4 offers a dual‐action alternative, combining bacteriostatic and bactericidal ...
Antoinette T. Nguyen   +2 more
wiley   +1 more source

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