Results 111 to 120 of about 333,575 (254)

Network Localization of Fatigue in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo   +12 more
wiley   +1 more source

Sliding coherence window technique for hierarchical detection of continuous gravitational waves

open access: yes, 2011
A novel hierarchical search technique is presented for all-sky surveys for continuous gravitational-wave sources, such as rapidly spinning nonaxisymmetric neutron stars. Analyzing yearlong detector data sets over realistic ranges of parameter space using
Pletsch, Holger J.
core   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

A Needle in a Cosmic Haystack: A Review of FRB Search Techniques

open access: yesUniverse
Ephemeral Fast Radio Bursts (FRBs) must be powered by some of the most energetic processes in the Universe. That makes them highly interesting in their own right, and as precise probes for estimating cosmological parameters.
Kaustubh M. Rajwade, Joeri van Leeuwen
doaj   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu   +11 more
wiley   +1 more source

Enhancing signal-to-noise ratio in active laser imaging under cloud and fog conditions through combined matched filtering and neural network

open access: yesFrontiers in Physics
Active laser imaging utilizes time-of-flight and echo intensity measurements to generate distance and intensity images of targets. However, scattering caused by cloud and fog particles, leads to imaging quality deterioration.
Chengshuai Cui   +3 more
doaj   +1 more source

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa   +10 more
wiley   +1 more source

Multi Detector Fusion of Dynamic TOA Estimation using Kalman Filter

open access: yes, 2015
In this paper, we propose fusion of dynamic TOA (time of arrival) from multiple non-coherent detectors like energy detectors operating at sub-Nyquist rate through Kalman filtering.
Dwivedi, Satyam   +2 more
core   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

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