Results 51 to 60 of about 298,992 (250)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

New digital demodulator with matched filters and curve segmentation techniques for BFSK demodulation: Analytical description

Ingeniería e Investigación, 2015
The present article relates in general to digital demodulation of Binary Frequency Shift Keying (BFSK). The objective of the present research is to obtain a new processing method for demodulating BFSK-signals in order to reduce hardware complexity in ...
Jorge Torres Gómez, Fidel Hernández, Joachim Habermann   +2 more
doaj   +1 more source

A dToF Ranging Sensor with Accurate Photon Detector Measurements for LiDAR Applications

Sensors, 2023
Direct time-of-flight (dToF) ranging sensors based on single-photon avalanche diodes (SPADs) have been used as a prominent depth-sensing devices. Time-to-digital converters (TDCs) and histogram builders have become the standard for dToF sensors. However,
Hengwei Yu, Long Wang, Jiqing Xu, Patrick Yin Chiang   +3 more
doaj   +1 more source

A blind implementation of multi-dimensional matched filtering in a Maximum-Likelihood receiver for SIMO channels [PDF]

, 2009
In order to establish the optimal receiver strategy, in terms of error rate for Single Input Multi Output (SIMO) wireless channels, the Maximum Likelihood (ML) detection should be performed following a multi-dimensional matched filter.
Coskun, A., Coskun, A., Kale, I., Kale, I.   +3 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Analog Frequency Tracking Filter

Advances in Electrical and Computer Engineering, 2013
This paper propose a new type of analog adaptive filter derived as a generalization of the concept of matched filter. We conceive such a filter to track the instantaneous frequency of frequency modulated signals.
ISAR, A., ISAR, D.
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Design and Implementation of a Low-Complexity Multi-h CPM Receiver with Linear Phase Approximation Synchronization Algorithm

Entropy, 2023
Multi-h continuous phase modulation (CPM), with extremely high spectral efficiency, involves the plague of high demodulation complexity with a large number of matched filters and a complex trellis.
Le Wang, Huan Wen, Xucen Wu, Qingping Song   +3 more
doaj   +1 more source

Adaptive matched filters for contrast imaging [PDF]

, 2010
2010 IEEE. Reprinted, with permission, from Sébastien Ménigot, Iulian Voicu, Anthony Novell, Melouka Elkateb Hachemi Amar and Jean-Marc Girault,Adaptive matched filters for contrast imaging, 2010 IEEE International Ultrasonics Symposium (IUS), 11---14 ...
Elkateb Hachemi Amar, Mélouka, Girault, Jean-Marc, Ménigot, Sébastien, Novell, Anthony, Voicu, Iulian   +4 more
core   +6 more sources