Results 61 to 70 of about 298,992 (250)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Matching Sensing to Actuation and Dynamics in Distributed Sensorimotor Architectures

open access: yesIEEE Access
In this article we explore the benefits of matching sensing characteristics to actuation and dynamics in the context of spatially distributed sensorimotor architectures, motivated by recently discovered connections in blowfly flight physics and visual ...
Zoe Turin   +4 more
doaj   +1 more source

Design and Evaluation of Optimal Orthogonal Wavelet With the Least Length of Wavelet Filters Using Spectral Matching

open access: yesIEEE Access, 2018
This paper presents a method to find a matched wavelet with the least length of wavelet filters using spectral matching. The existing problem in algorithm of designing in spectral fashion is described, and the corresponding solution is provided.
Mahmoud Mansouri Jam, Hamed Sadjedi
doaj   +1 more source

Summed Parallel Infinite Impulse Response (SPIIR) Filters For Low-Latency Gravitational Wave Detection [PDF]

open access: yes, 2011
With the upgrade of current gravitational wave detectors, the first detection of gravitational wave signals is expected to occur in the next decade.
A. V. Oppenheim   +8 more
core   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Matching-CNN Meets KNN: Quasi-Parametric Human Parsing

open access: yes, 2015
Both parametric and non-parametric approaches have demonstrated encouraging performances in the human parsing task, namely segmenting a human image into several semantic regions (e.g., hat, bag, left arm, face).
Cao, Xiaochun   +8 more
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

FDA-MIMO Beampattern Synthesis with Hamming Window Weighted Linear Frequency Increments

open access: yesInternational Journal of Aerospace Engineering, 2020
By utilizing a tiny frequency increment across the array elements, frequency diverse array (FDA) generates a beampattern possessing the property of range-angle-dependent.
Ming Tan   +4 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

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