Results 181 to 190 of about 2,234,974 (362)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Information Reuse Methods for Multi-Dimensional Models in Discrete Workshops
With the gradual development of digital twin technology from theory to practice, the importance of the efficient reuse of existing digital twin models has become increasingly prominent in order to reduce the waste of resources and additional costs caused
Ruiping Luo, Jiaxing Zhu
doaj +1 more source
Beyond Bags of Features: Spatial Pyramid Matching for Recognizing Natural Scene Categories
Svetlana Lazebnik +2 more
semanticscholar +1 more source
Deadlines and fixed end dates are pervasive in matching markets including school choice, the market for new graduates, and even financial markets such as the market for federal funds. Deadlines drive fundamental non-stationarity and complexity in behavior, generating significant departures from the steady-state equilibria usually studied in the search ...
openaire +3 more sources
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Contractual Structure and Endogenous Matching in Partnershipso [PDF]
We analyze optimal contracts and optimal matching patterns in a simple model of partnership where there is a double-sided moral hazard problem and potential partners differ in their productivity in two tasks.
Alexander Karaivanov, Maitreesh Ghatak
core
Diversified Top-k Graph Pattern Matching [PDF]
Graph pattern matching has been widely used in e.g., social data analysis. A number of matching algorithms have been developed that, given a graph pattern Q and a graph G, compute the set M(Q;G) of matches of Q in G.
Wang, Xin +2 more
core
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Signal Recovery From Random Measurements Via Orthogonal Matching Pursuit
J. Tropp, Anna C. Gilbert
semanticscholar +1 more source

