IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
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Patient-reported outcomes after lateral unicompartmental and total knee arthroplasty: a propensity score-matched cohort study. [PDF]
Hariri M +7 more
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Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada +7 more
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The impact of maternal hepatitis B virus infection on IVF/ICSI-assisted pregnancy outcomes: a propensity score-matched cohort study. [PDF]
Jiang W +5 more
europepmc +1 more source
Non-Linear Association Between Intraoperative Remifentanil Infusion and Postoperative Opioid Consumption After Uniportal VATS: A Propensity-Matched Retrospective Cohort Study. [PDF]
Zhu Y, Xu S, Luo L, Li C, Wu J.
europepmc +1 more source
Harmonizing Peak Matching between Multidimensional NMR Spectra. [PDF]
Bishop AC +4 more
europepmc +1 more source
A Distributed 4-Port Hilbert Slot MIMO Antenna with Full-Body Phantom Validation for mmWave Wearable Telemetry. [PDF]
Saleh S, Saeidi T, Timmons N.
europepmc +1 more source
Comparable outcomes after McKeown and Ivor-Lewis minimally invasive esophagectomy with standardized two-field lymphadenectomy: a propensity score-matched study. [PDF]
Quan S +5 more
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