Results 201 to 210 of about 1,846,953 (347)

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Trajectories of cognitive decline before and after new-onset dual sensory impairment: findings from two longitudinal studies. [PDF]

Alzheimers Dement
Zou M, Gong H, Chen B, Chen S, Teng J, Zhou J, Shao J, Zhang Y, Cai F, Huang P.   +9 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

IllumiSIFT: A Cascade Framework for DoG Pyramid Learning in Darkness. [PDF]

Sensors (Basel)
Noor DF, Chowdhury MR, Sikder S.
europepmc   +1 more source

Single-Round Pattern Matching Key Generation Using Physically Unclonable Function [PDF]

, 2019
Yuichi Komano, Kazuo Ohta, Kazuo Sakiyama, Mitsugu Iwamoto, Ingrid Verbauwhede   +4 more
openalex   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Real-World Effectiveness of Tolvaptan for Hyponatremia in Cirrhosis Across Global Regions: A Target Trial Emulation. [PDF]

JGH Open
Okushin K, Tateishi R, Fujishiro M, Tsutsumi T, Koike K, Tanaka T.   +5 more
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Association Between Perioperative Dexmedetomidine Exposure and Post-Transplant Renal Outcomes: A Retrospective Analysis. [PDF]

Drug Des Devel Ther
Hung KC, Yu TS, Ho CN, Yu CH, Lai YC, Chang YJ, Chen IW.   +6 more
europepmc   +1 more source

Stereo matching: Evaluation of three algorithms and two cost functions

, 2012
Victor Jacob Jordan
openalex   +1 more source