Results 191 to 200 of about 458,841 (313)

Fine-grained sketch-based image retrieval by matching deformable part models

, 2014
(c) 2014. The copyright of this document resides with its authors. It may be distributed unchanged freely in print or electronic forms.© 2014. The copyright of this document resides with its authors.
Song, YZ, Timothy M. Hospedales, Li, Y, Yi Li, Shaogang Gong, Hospedales, TM, Gong, S, Yi-zhe Song   +7 more
core  

Response to 'Impact of control selection strategies on GWAS results: a study of prostate cancer in the UK Biobank'. [PDF]

Brief Bioinform
Law PJ, Went M, Houlston RS.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

A Multimodal Representation Learning Framework for Molecular Graph and NMR Spectrum Alignment. [PDF]

Entropy (Basel)
Li X, Wang X, Liu ZM, Liu JB, Huang X.
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Assessing the factors influencing the quality of pocket-conditioned 3D generative models. [PDF]

J Cheminform
Wang K, Lai H, Irwin R, Janet JP, Tibo A.   +4 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

The choice of time scales in survival analysis has implications: calendar time versus patients' time-to-event. [PDF]

BMC Med Res Methodol
Vilsmeier J, Büchele G, Rehm M, Unseld T, Rothenbacher D, Beyersmann J.   +5 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Association between hypnotic medication use and in-hospital falls among older adults: A multicenter landmark analysis. [PDF]

PLoS One
Nishino T, Kubota Y, Miyagi Y, Tanabe N, Yamaguchi F, Ito H, Soh S, Yano A, Mizuno M, Kim C, Ishii Y, Kondo Y, Asai K.   +12 more
europepmc   +1 more source