Matching between typical fluctuations and large deviations in disordered systems: application to the statistics of the ground state energy in the SK spin-glass model [PDF]
, 2010 Cécile Monthus, Thomas Garel
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Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
The German turnover tax statistics panel [PDF]
Based on the yearly turnover tax statistics, the German turnover tax statistics panel allows for the first time detailed longitudinal analyses of nearly all economic sectors. In addition to turnover tax related variables, the dataset provides information
Alexander Vogel, Stefan Dittrich
core
Data Integration: Techniques and Evaluation [PDF]
, 2004 Within the DIECOFIS framework, ec3, the Division of Business Statistics from the Vienna University of Economics and Business Administration and ISTAT worked together to find methods to create a comprehensive database of enterprise data required for ...
Denk, Michaela, Hackl, Peter
core
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
String Matching Techniques: An Empirical Assessment Based on Statistics Austria's Business Register [PDF]
, 2005 The maintenance and updating of Statistics Austria's business register requires a regularly matching of the register against other data sources; one of them is the register of tax units of the Austrian Federal Ministry of Finance. The matching process
Denk, Michaela +2 more
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
The essential role of balance tests in propensity‐matched observational studies: Comments on ‘A critical appraisal of propensity‐score matching in the medical literature between 1996 and 2003’ by Peter Austin, Statistics in Medicine [PDF]
, 2008 Bjarke Brandt Hansen
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Impact of matching error on linked mortality outcome in a data linkage of secondary mental health data with Hospital Episode Statistics (HES) and mortality records in South East London: a cross-sectional study [PDF]
, 2020 Amelia Jewell +5 more
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