Results 121 to 130 of about 3,188,344 (333)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Male attractiveness in fruit flies is influenced by previous exposure of females to males of different attractiveness

Scientific Reports
Mate choice is a crucial decision in any animal. In terms of fitness, the best mate is the one that leads to the most abundant and productive offspring.
Laure-Anne Poissonnier, Etienne Danchin, Guillaume Isabel   +2 more
doaj   +1 more source

Excitation and inhibition onto central courtship neurons biases Drosophila mate choice

eLife, 2015
The ability to distinguish males from females is essential for productive mate selection and species propagation. Recent studies in Drosophila have identified different classes of contact chemosensory neurons that detect female or male pheromones and ...
Benjamin R. Kallman, Heesoo Kim, Kristin Scott   +2 more
semanticscholar   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Male mate choice in Tibetan macaques Macaca thibetana at Mt. Huangshan, China

Current Zoology, 2010
Though females are generally more selective in mate choice, males may also benefit from mate choice if male reproductive success is limited by factors other than simply the number of female mates, and if females differ in short-term reproductive ...
Min ZHANG, Jinhua LI, Yong ZHU, Xi WANG, Su WANG
doaj  

Stylish lengths: Mate choice in flowers [PDF]

, 2011
The styles of flowers may represent an arena for pollen competition in the race to fertilize ovules. Accordingly, selection should favour a longer 'race' to better discriminate among variable pollen by increasing style length.
Ganeshaiah, KN, Jaboury , Ghazoul, Ramesha, BT, Ravikanth, G, Uma Shaanker, R, Yetish, MD   +5 more
core   +2 more sources

Free mate choice enhances conservation breeding in the endangered giant panda

Nature Communications, 2015
Conservation breeding programmes have become an increasingly important tool to save endangered species, yet despite the allocation of significant resources, efforts to create self-sustaining populations have met with limited success.
Meghan S Martin-Wintle, D. Shepherdson, Guiquan Zhang, He-min Zhang, Desheng Li, Xiaoping Zhou, Rengui Li, R. Swaisgood   +7 more
semanticscholar   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Self-Perceived Mate Value, Facial Attractiveness, and Mate Preferences: Do Desirable Men Want It All?

Evolutionary Psychology, 2018
Ten years ago, Buss and Shackelford demonstrated that high mate value (i.e., physically attractive) women held more discerning mate preferences relative to lower mate value women.
Steven Arnocky
doaj   +1 more source

An Mhc Component to Kin Recognition and Mate Choice in Birds: Predictions, Progress, and Prospects [PDF]

, 2002
The major histocompatibility complex (Mhc) has been identified as a locus influencing disease resistance, mate choice, and kin recognition in mammals and fish. However, it is unclear whether the mechanisms by which Mhc genes influence behavior in mammals
Edwards, Scott, Zelano, Bethanne
core   +1 more source