Results 161 to 170 of about 1,735,594 (277)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

A lot of variation and asymmetry in the white patches of male capercaillie tails, but no association with mate choice. [PDF]

Ecol Evol
Milonoff M, Paasivaara A.
europepmc   +1 more source

Remodeling male coercion and the evolution of sexual autonomy by mate choice. [PDF]

Evolution, 2023
Snow SS, Prum RO.
europepmc   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Determining behavioral proxies of preference: mate choice and the New England Cottontail (<i>Sylvilagus transitionalis</i>). [PDF]

J Mammal
Petit H, Stansell V, Perrotti L, Richard JT.   +3 more
europepmc   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The Eye of the Beholder: Male Mate Choice Is Influenced by Partner Infection Status and Self-Condition. [PDF]

Ecol Evol
Castillo C, Meneses Placencia J, Ulloa J, Cordero-Molina S, Macías García C, Krams I, Contreras-Garduño J.   +6 more
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Exposure to Rivals Does Not Affect Male Mate Choice in <i>Drosophila melanogaster</i>. [PDF]

Ecol Evol
Shankar H, Lev A, Halpern RS, Hassan T, Jiang M, Martinez IM, Robinson KL, Subramaniam LE, Zackai R, Pischedda A.   +9 more
europepmc   +1 more source

The effect of individual state on the strength of mate choice in females and males. [PDF]

Behav Ecol, 2023
Dougherty LR.
europepmc   +1 more source